Streptococcus pneumoniae strain NTPn 119

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain NTPn 119 is a Gram-positive, non-motile cocci bacterium that typically arranges itself in chains or pairs. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 30°C, and possesses a single membrane and one replicon. The habitat of S. pneumoniae NTPn 119 is diverse, as it is found in multiple environments. It exhibits a free-living biotic relationship, but it is primarily pathogenic to various hosts, including humans (Homo sapiens), chickens (Gallus gallus), guinea pigs (Cavia), and other small mammals like the Meriones unguiculatus and Chinchilla. This strain is associated with a range of significant health effects, including bacteremia, pneumonia, meningitis, and various infections such as sepsis, cellulitis, and acute otitis media. It is particularly notable for its role in community-acquired pneumonia (CAP) and invasive pneumococcal disease (IPD), which can lead to severe complications like purulent pericarditis and septicemia. The pathogenicity of S. pneumoniae NTPn 119 underscores its importance in human health, particularly as a leading cause of respiratory and systemic infections. Understanding its ecological adaptability and pathogenic potential contributes to the broader knowledge of bacterial infections and their implications for public health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain NTPn 119

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain NTPn 119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain NTPn 119 NTPn_119_contig_99, whole

Gene Summary

Adenine Count

646752 bp

Thymine Count

644665 bp

Guanine Count

427629 bp

Cytosine Count

428087 bp

Genome Length

2147347 bp

Protein-coding Genes

1968 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidine kinaseAZJ05_05295Not AvailablePositive1977490 - 197882450676.3
hypothetical proteinAZJ05_05300Not AvailableNegative1978858 - 197914510984.6
peptidase u32AZJ05_05305Not AvailablePositive1979285 - 198021435534.2
atp-dependent dna helicaseAZJ05_05310Not AvailablePositive1980414 - 198286493513.3
rod shape-determining protein rodaAZJ05_05315Not AvailablePositive1982901 - 198412445237.1
4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis proteinAZJ05_05320Not AvailablePositive1984135 - 198468920233.1
dna gyrase subunit bAZJ05_05325Not AvailablePositive1984774 - 198533721115.9
dna topoisomerase iv subunit bAZJ05_05330Not AvailablePositive1985352 - 198729872272.7
septation ring formation regulator ezraAZJ05_05335Not AvailablePositive1987380 - 198910766582.1
hypothetical proteinAZJ05_05470Not AvailableNegative2010765 - 201122617678.7

Displaying genes 1921 – 1930 of 2045 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total