Streptococcus mitis strain CMW7705B

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain CMW7705B is a Gram-positive bacterium characterized by its cocci shape and arrangements typically found in chains or pairs. This strain is classified as a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which is consistent with its sedentary lifestyle. The habitat of S. mitis strain CMW7705B is primarily host-associated, specifically within Homo sapiens, indicating its role as a commensal organism in human microbiota. However, it also has significant clinical implications, as it is associated with various health issues, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations highlight its potential pathogenicity under certain conditions. S. mitis strain CMW7705B is mesophilic, indicating that it thrives at moderate temperatures. The strain maintains a simple genomic structure with one replicon and a single membrane, which is characteristic of many bacteria in its genus. Importantly, it is a nonsporulating organism, indicating it does not form spores. The ecological insight regarding S. mitis strain CMW7705B is its dual role as a free-living organism and a potential pathogen. While it can be part of the normal human microbiota, its ability to cause invasive diseases underscores the importance of understanding its behavior in different environments, particularly in clinical settings where it may shift from a benign to a pathogenic state.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain CMW7705B

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain CMW7705B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain CMW7705B


Gene Summary

Adenine Count

567873 bp

Thymine Count

570843 bp

Guanine Count

375019 bp

Cytosine Count

383592 bp

Genome Length

1897327 bp

Protein-coding Genes

1924 genes

Non-Coding Genes

71 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttrNot AvailableNot AvailablePositive982493 - 982506Not Available
AttlNot AvailableNot AvailablePositive1380917 - 1380928Not Available
Gp273HMPREF3228_01416Not AvailableNegative1381450 - 138222329646.7
Nicotinamide mononucleotide transporterHMPREF3228_01417Not AvailableNegative1382225 - 138300430066.6
Nicotinamide-nucleotide adenylyltransferaseHMPREF3228_01418Not AvailableNegative1383014 - 138407241084.5
Atp-dependent clp protease atp-binding subunitHMPREF3228_01419Not AvailableNegative1384210 - 138664290184.1
putative transcriptional regulator ctsrHMPREF3228_01420Not AvailableNegative1386644 - 138710217528.2
hypothetical proteinHMPREF3228_01421Not AvailableNegative1387439 - 13876578157.86
Hypothetical proteinHMPREF3228_01422Not AvailableNegative1388091 - 138860320294.8
hypothetical proteinHMPREF3228_01423Not AvailableNegative1388856 - 138938621421.4

Displaying genes 31 – 40 of 1995 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total