Streptococcus mitis strain CMW7705B

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain CMW7705B is a Gram-positive bacterium characterized by its cocci shape and arrangements typically found in chains or pairs. This strain is classified as a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which is consistent with its sedentary lifestyle. The habitat of S. mitis strain CMW7705B is primarily host-associated, specifically within Homo sapiens, indicating its role as a commensal organism in human microbiota. However, it also has significant clinical implications, as it is associated with various health issues, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations highlight its potential pathogenicity under certain conditions. S. mitis strain CMW7705B is mesophilic, indicating that it thrives at moderate temperatures. The strain maintains a simple genomic structure with one replicon and a single membrane, which is characteristic of many bacteria in its genus. Importantly, it is a nonsporulating organism, indicating it does not form spores. The ecological insight regarding S. mitis strain CMW7705B is its dual role as a free-living organism and a potential pathogen. While it can be part of the normal human microbiota, its ability to cause invasive diseases underscores the importance of understanding its behavior in different environments, particularly in clinical settings where it may shift from a benign to a pathogenic state.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain CMW7705B

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain CMW7705B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain CMW7705B

Gene Summary

Adenine Count

567873 bp

Thymine Count

570843 bp

Guanine Count

375019 bp

Cytosine Count

383592 bp

Genome Length

1897327 bp

Protein-coding Genes

1924 genes

Non-Coding Genes

71 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
issag9, transposase family proteinHMPREF3228_01208Not AvailableNegative1184874 - 118567630887.5
glycosyltransferase, group 2 family proteinHMPREF3228_01209Not AvailablePositive1186055 - 118707139107.0
signal peptide protein, ysirk familyHMPREF3228_01210Not AvailablePositive1187187 - 118813133366.2
transcriptional regulator comx1HMPREF3228_01211Not AvailableNegative1188186 - 118866519886.6
signal peptide protein, ysirk familyHMPREF3228_01212Not AvailableNegative1188781 - 1194409200222.0
lpxtg-motif protein cell wall anchor domain proteinHMPREF3228_01213Not AvailableNegative1194970 - 119755991949.1
g5 domain proteinHMPREF3228_01214Not AvailableNegative1197560 - 119823524050.6
lpxtg-motif protein cell wall anchor domain proteinHMPREF3228_01215Not AvailablePositive1198238 - 119930536584.8
glycosyl hydrolase, family 92HMPREF3228_01216Not AvailableNegative1199419 - 120045939187.9
hypothetical proteinHMPREF3228_01217Not AvailableNegative1200456 - 120151440570.9

Displaying genes 1241 – 1250 of 1995 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total