Gardnerella vaginalis strain GED7760B

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis strain GED7760B is a Gram-positive, non-motile rod-shaped bacterium that is classified as a chemoheterotroph. This strain is anaerobic, meaning it thrives in environments devoid of oxygen, and it is mesophilic, with an optimal growth temperature of 37°C. The organism has a single membrane and contains one replicon. This strain is primarily associated with hosts such as Homo sapiens and other metazoans, including Oryctolagus cuniculus (the domestic rabbit). Gardnerella vaginalis is known for its role in various health-related conditions, particularly in humans, where it is implicated in urinary tract infections (UTIs), pyogenic osteomyelitis, and bacterial vaginosis (BV). Its pathogenic potential contributes to its significance in the study of human microbiomes and related health issues. Gardnerella vaginalis strain GED7760B is free-living and does not form spores, which is characteristic of many bacteria that inhabit specific niches within the host. The presence of this strain in the microbiota highlights its ecological role and potential impact on host health, particularly in maintaining the balance of the vaginal microbiome. The association with BV underscores the importance of understanding such microorganisms in clinical settings, as imbalances can lead to significant health complications.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
Strainstrain GED7760B

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis strain GED7760B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Gardnerella vaginalis strain GED7760B

Gene Summary

Adenine Count

416256 bp

Thymine Count

426458 bp

Guanine Count

322926 bp

Cytosine Count

320011 bp

Genome Length

1485651 bp

Protein-coding Genes

1272 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribonucleoside-diphosphate reductase, alpha subunitHMPREF3216_00961Not AvailableNegative1070450 - 107268483700.7
nrdi proteinHMPREF3216_00962Not AvailableNegative1072750 - 107325018523.1
glutaredoxinHMPREF3216_00963Not AvailableNegative1073308 - 10735689613.23
phosphogluconate dehydrogenaseHMPREF3216_00964Not AvailablePositive1074001 - 107546152862.8
6-phosphogluconolactonaseHMPREF3216_00965Not AvailableNegative1075564 - 107638530385.0
putative opca proteinHMPREF3216_00966Not AvailableNegative1076427 - 107742536612.4
glucose-6-phosphate dehydrogenaseHMPREF3216_00967Not AvailableNegative1077422 - 107901159226.4
acyltransferaseHMPREF3216_00968Not AvailableNegative1079061 - 108131983228.0
hypothetical proteinHMPREF3216_00969Not AvailableNegative1081448 - 10816096355.13
inorganic diphosphataseHMPREF3216_00970Not AvailablePositive1081822 - 108231618394.6

Displaying genes 961 – 970 of 1322 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic osteomyelitisCausesPMC7852921
Bacterial vaginosisCausesPMC11597594
Bacterial vaginosisCausesPMC11782042
UtisCausesPMC11782042
Bacterial vaginosisCausesPMC12054147
BvCausesPMC12519793
BvCausesPMC12800088
Bacterial vaginosisCausesPMC13228082
BvCausesPMC13228082
Bacterial vaginosisCausesPMC12281154

Displaying health effects 1 – 10 of 11 in total