Enterococcus faecium strain MJR8396B

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain MJR8396B is a Gram-positive, facultative anaerobic coccus primarily found in fermented mare milk. This strain possesses a single replicon and is notable for its pathogenic potential in humans, contributing to various health issues, including endocarditis, bloodstream infections, urinary tract infections, and biliary tract infections. It has also been associated with nosocomial infections and bacteremia, highlighting its importance in clinical microbiology. The strain has a diverse range of hosts that includes Homo sapiens, Gallus gallus, Bos taurus, and several others across different animal classes such as Metazoa, Aves, and Mammalia. This broad host range suggests that E. faecium strain MJR8396B may have evolved mechanisms to adapt to various environments, facilitating its survival and pathogenicity. The presence of flagella in this strain may contribute to its motility and colonization abilities, although specific functions in this context have not been detailed. The ability of E. faecium to thrive in both aerobic and anaerobic conditions may also enhance its survival in different host environments. Given its role in human infections and its presence in fermented dairy products, E. faecium strain MJR8396B serves as a significant example of the dual nature of certain microorganisms, which can be both beneficial in food fermentation and harmful as pathogens. This duality underscores the complexity of microbial interactions in both ecological and clinical settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain MJR8396B

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain MJR8396B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain MJR8396B

Gene Summary

Adenine Count

812140 bp

Thymine Count

826306 bp

Guanine Count

501950 bp

Cytosine Count

510492 bp

Genome Length

2650888 bp

Protein-coding Genes

2743 genes

Non-Coding Genes

72 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter, atp-binding proteinHMPREF3199_02409Q9S472Negative2278239 - 227976556772.9
hypothetical proteinHMPREF3199_02410P25548Negative2279819 - 22799956534.39
putative multiple sugar-binding periplasmic protein sbpaHMPREF3199_02411P54083Negative2280092 - 228090729016.4
hypothetical proteinHMPREF3199_02412Not AvailablePositive2280977 - 22810964788.95
hypothetical proteinHMPREF3199_02413Not AvailablePositive2281134 - 228214438117.8
atpase/histidine kinase/dna gyrase b/hsp90 domain proteinHMPREF3199_02414O31516Positive2282158 - 228360955256.2
transcriptional regulator, arac familyHMPREF3199_02415Q8D4U6Positive2283602 - 228516759824.8
oxidoreductase, aldo/keto reductase family proteinHMPREF3199_02416P42972Negative2285301 - 228621534344.2
phosphoribosylamine--glycine ligaseHMPREF3199_02417Q92AP4Negative2286338 - 228761245955.1
phosphoribosylaminoimidazolecarboxamide formyltransferase/imp cyclohydrolaseHMPREF3199_02418Q833Z3Negative2287628 - 228916356865.1

Displaying genes 2411 – 2420 of 2815 in total

Metabolites

114 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000433malonateC3H2O4Chemical structure of malonateNot available
Average102.0456Da
Monoisotopic101.9953086Da
BASm0000542HgHgChemical structure of HgNot available
Average200.59Da
Monoisotopic201.9706256Da
BASm00008001,8-diazacyclotetradecane-2,9-dioneC12H22N2O2Chemical structure of 1,8-diazacyclotetradecane-2,9-dioneNot available
Average226.32Da
Monoisotopic226.168127956Da

Displaying 1–10 of 114 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total