Escherichia coli strain GN02766 000001F_arrow

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain GN02766 000001F_arrow is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments. It is mesophilic, with an optimal growth temperature of 37°C. The strain is host-associated and has a diverse range of potential hosts, including Homo sapiens, various livestock (e.g., Bos taurus, Sus scrofa), and other vertebrates such as Aves and Primates, as well as plants like Solanum lycopersicum and Brassica oleracea var. italica. This broad host range highlights its adaptability and ecological versatility. E. coli GN02766 is known to be free-living, indicating it can exist independently outside of host organisms, while also causing numerous health effects in humans and animals. These effects include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemolytic uremic syndrome (HUS) and bacterial meningitis. The strain is implicated in various diseases, including diarrheal diseases, septicemia, and even complications leading to neonatal mortality. The pathogenicity of E. coli strain GN02766 in humans suggests its significant role in public health, particularly concerning foodborne illnesses and infections. Its capacity to thrive in multiple environments and hosts emphasizes the importance of monitoring this strain in both clinical and environmental settings to mitigate its potential health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain GN02766 000001F_arrow

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain GN02766 000001F_arrow
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain GN02766 000001F_arrow, whole genome

Gene Summary

Adenine Count

1337866 bp

Thymine Count

1343168 bp

Guanine Count

1366160 bp

Cytosine Count

1360922 bp

Genome Length

5408116 bp

Protein-coding Genes

4611 genes

Non-Coding Genes

606 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
colibactin hybrid non-ribosomal peptide synthetase/type i polyketide synthase clbbAWF59_018650Not AvailablePositive3789486 - 3799106352570.0
colibactin polyketide synthase clbcAWF59_018655Not AvailablePositive3799147 - 380174794649.4
colibactin biosynthesis dehydrogenase clbdAWF59_018660Not AvailablePositive3801757 - 380262632488.4
colibactin biosynthesis aminomalonyl-acyl carrier protein clbeAWF59_018665Not AvailablePositive3802656 - 38029049474.53
colibactin biosynthesis dehydrogenase clbfAWF59_018670Not AvailablePositive3802908 - 380403841196.1
colibactin biosynthesis acyltransferase clbgAWF59_018675Not AvailablePositive3804035 - 380530346720.0
colibactin non-ribosomal peptide synthetase clbhAWF59_018680Not AvailablePositive3805351 - 3810147176792.0
colibactin non-ribosomal peptide synthetase clbjAWF59_018690Not AvailablePositive3813272 - 3819772242898.0
colibactin hybrid non-ribosomal peptide synthetase/type i polyketide synthase clbkAWF59_018695Not AvailablePositive3819783 - 3826247237813.0
colibactin biosynthesis amidase clblAWF59_018700Not AvailablePositive3826240 - 382770353515.7

Displaying genes 3851 – 3860 of 5217 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total