Haemophilus influenzae biotype aegyptius strain F3042

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae biotype aegyptius strain F3042 is a Gram-negative, rod-shaped bacterium that exhibits both aerobic and facultatively anaerobic growth, indicating its ability to thrive in varying oxygen environments. This strain is non-motile and possesses true flagella, which is notable for a bacterium of its kind. It is categorized as mesophilic, with an optimal growth temperature of 35°C. H. influenzae biotype aegyptius is primarily host-associated, specifically infecting Homo sapiens. Its biotic relationships are predominantly free-living, though it is capable of causing a wide range of health issues in humans. Documented health effects include severe conditions such as bacteremia, pneumonia, meningitis, necrotizing fasciitis, and sepsis. Additionally, it is associated with community-acquired pneumonia, respiratory infections, ear infections (otitis media), and exacerbations of chronic pulmonary diseases, including chronic obstructive pulmonary disease (COPD). The strain's ability to cause both invasive and non-invasive diseases underscores its pathogenic potential and adaptability within human hosts. Given its diverse range of health effects, H. influenzae biotype aegyptius strain F3042 plays a significant role in respiratory and systemic infections, particularly in vulnerable populations. This highlights the importance of continued monitoring and study of this bacterium to better understand its impact on human health and to develop effective treatment strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
Strainbiotype aegyptius strain F3042

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae biotype aegyptius strain F3042
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus influenzae biotype aegyptius strain F3042 contig_137,

Gene Summary

Adenine Count

608820 bp

Thymine Count

611574 bp

Guanine Count

377912 bp

Cytosine Count

371351 bp

Genome Length

1969657 bp

Protein-coding Genes

1718 genes

Non-Coding Genes

187 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Head morphogenesis proteinAO052_00770Not AvailableNegative140887 - 14175433093.5
TerminaseAO052_00780Not AvailableNegative143439 - 14508862535.3
Conserved possible dna-binding proteinAO052_00785Not AvailableNegative145238 - 14573818778.4
hypothetical proteinAO052_00790Not AvailableNegative145740 - 1460069568.7
Hypothetical proteinAO052_00795Not AvailableNegative146006 - 1462639899.02
hypothetical proteinAO052_00800Not AvailableNegative146387 - 1466449908.11
Hypothetical proteinAO052_00805Not AvailableNegative146644 - 14693410741.8
Hypothetical proteinAO052_00810Not AvailableNegative147088 - 14759118809.7
Hypothetical proteinAO052_00815Not AvailableNegative147672 - 14810016424.9
Toxin-antitoxin system antitoxin component hicbAO052_00820Not AvailableNegative148212 - 14862815305.4

Displaying genes 1 – 10 of 1905 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

323 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da

Displaying 1–10 of 323 metabolites

Health Effects

Health ConditionRelationReference
Ear infection (otitis media)CausesPMC10964412
Lung infection (pneumonia)CausesPMC10964412
Exacerbations of chronic pulmonary diseases (e.g., chronic obstructive pulmonary disease, protracted bacterial bronchitis, and bronchiectasis)CausesPMC10964412
Ear infectionCausesPMC10964412
Otitis mediaCausesPMC10964412
Lung infectionCausesPMC10964412
PneumoniaCausesPMC10964412
Invasive diseaseCausesPMC10964412
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026

Displaying health effects 1 – 10 of 60 in total