Lacticaseibacillus paracasei strain FAM18172

Gram-positiveRodNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Lactobacillaceae

Genus

Lacticaseibacillus

Description

Lacticaseibacillus paracasei strain FAM18172 is a rod-shaped, Gram-positive bacterium characterized by its arrangement in chains. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It is non-motile and does not possess flagella. The optimal growth temperature for this strain is 30°C, falling within the mesophilic temperature range. Lacticaseibacillus paracasei strain FAM18172 has a single replicon and a single membrane, which is typical for many bacteria within its classification. This strain is free-living and has been identified in various habitats, suggesting its adaptability to different ecological niches. Notably, this strain has been associated with hosts including Homo sapiens, Oryctolagus cuniculus (the European rabbit), and Panax ginseng (a medicinal plant). This highlights its potential significance in both human health and the broader ecosystem, as it may interact with a variety of organisms. One health-related aspect of Lacticaseibacillus paracasei strain FAM18172 is its involvement in graft-versus-host disease (GvHD), a condition that can occur after a stem cell or bone marrow transplant. This association suggests that the strain may play a role in modulating immune responses, which could have implications for therapeutic applications. The strain's free-living nature and versatile habitat preferences indicate a robust ecological role, contributing to microbial diversity and potentially influencing host health in various environments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusLacticaseibacillus
SpeciesLacticaseibacillus paracasei
Strainstrain FAM18172

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lacticaseibacillus paracasei strain FAM18172
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Oryctolagus cuniculus, Panax ginseng
Cell arrangementChains
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Lacticaseibacillus paracasei strain FAM18172

Gene Summary

Adenine Count

822892 bp

Thymine Count

816848 bp

Guanine Count

706893 bp

Cytosine Count

705678 bp

Genome Length

3052779 bp

Protein-coding Genes

2901 genes

Non-Coding Genes

179 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2-oxoisovalerate dehydrogenase subunit alphaFAM18172_01535Not AvailableNegative1479227 - 148023137017.5
dihydrolipoyl dehydrogenaseFAM18172_01536Not AvailableNegative1480249 - 148166450204.1
butyrate kinase 2FAM18172_01537Not AvailableNegative1481661 - 148278240017.4
phosphate acetyltransferaseFAM18172_01538Not AvailableNegative1482779 - 148363029971.4
orotate phosphoribosyltransferaseFAM18172_01539Not AvailableNegative1484193 - 148483422544.1
orotidine 5'-phosphate decarboxylaseFAM18172_01540Not AvailableNegative1484827 - 148554625511.0
dihydroorotate dehydrogenase b (nad(+)), catalytic subunitFAM18172_01541Not AvailableNegative1485543 - 148641829771.3
carbamoyl-phosphate synthase large chainFAM18172_01542Not AvailableNegative1486579 - 1489761116022.0
carbamoyl-phosphate synthase small chainFAM18172_01543Not AvailableNegative1489764 - 149084639403.0
dihydroorotaseFAM18172_01544Not AvailableNegative1491006 - 149227145115.0

Displaying genes 1531 – 1540 of 3080 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GvhdCausesPMC10757094

Displaying health effects 1 – 1 of 1 in total