Escherichia coli strain CFSAN026843

Escherichia coli strain CFSAN026843 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C, and can be found in pairs or singles within its habitat, which is primarily host-associated. The strain has a single replicon and two membranes, indicating its classification as a typical member of the Enterobacteriaceae family. It exhibits a free-living biotic relationship, suggesting its ability to survive independently while also being associated with various hosts. Notably, CFSAN026843 has been linked to a wide range of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus) and cattle (Bos taurus), as well as various other mammals and even plants like tomatoes (Solanum lycopersicum). CFSAN026843 is associated with numerous health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The strain's pathogenicity in humans underscores its role as a significant public health concern, leading to various clinical manifestations ranging from mild diarrhea to severe systemic infections. Ecologically, CFSAN026843's widespread presence across different hosts and environments highlights its adaptability and potential for transmission. Its association with both human health and agricultural animals indicates that monitoring and controlling this strain is crucial for preventing foodborne illnesses and ensuring public health safety.