Klebsiella pneumoniae strain CHS153

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain CHS153 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles. It is motile, possessing flagella, and thrives optimally at 37°C within a mesophilic temperature range. K. pneumoniae CHS153 is primarily found in host-associated environments, indicating a close relationship with various organisms. Its known hosts include Homo sapiens, Gallus gallus (chickens), and several other metazoans, as well as plants and other vertebrates. This diverse range of hosts suggests that the strain can adapt to different biological systems, highlighting its ecological versatility. Notably, K. pneumoniae CHS153 is associated with a wide array of health effects in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its pathogenicity is significant, as it contributes to severe conditions such as sepsis and neonatal sepsis, as well as localized infections like liver abscesses and endophthalmitis. In summary, K. pneumoniae strain CHS153 exemplifies a free-living bacterium with a complex biotic relationship with its hosts, capable of causing a range of infections. Its presence in both animal and plant hosts indicates potential ecological implications, particularly in understanding the transmission dynamics of pathogenic bacteria in various environments. The strain's adaptability and pathogenic potential underscore the importance of monitoring such organisms in clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain CHS153

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain CHS153
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain CHS153 aetzk-supercont1.7.C19, whole

Gene Summary

Adenine Count

1209544 bp

Thymine Count

1207239 bp

Guanine Count

1580664 bp

Cytosine Count

1644802 bp

Genome Length

5642249 bp

Protein-coding Genes

4966 genes

Non-Coding Genes

463 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinSK89_04889Not AvailableNegative5080071 - 50803409579.68
pimeloyl-[acyl-carrier protein] methyl esteraseSK89_04890A6TF35Negative5080461 - 508123428295.5
gluconate transporter periplasmic gluconate-binding proteinSK89_04891Q8Z222Positive5081273 - 508194725367.3
fe/s biogenesis protein nfuaSK89_04892B5XTS2Positive5082006 - 508258121005.8
high-affinity gluconate transporterSK89_04893P39835Positive5082918 - 508423446138.8
4-alpha-glucanotransferaseSK89_04894P15977Negative5084337 - 508643078544.7
maltodextrin phosphorylaseSK89_04895P00490Negative5086441 - 508883190064.4
hth-type transcriptional regulator maltSK89_04896A6TF41Positive5089456 - 5092161103117.0
glycerol-3-phosphate regulon repressorSK89_04897P0ACL0Negative5092177 - 509293527912.5
rhomboid protease glpgSK89_04898A6TF43Negative5092985 - 509380930865.6

Displaying genes 4941 – 4950 of 5429 in total

Metabolites

1580 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002634-(hydroxymethyl)benzenesulfonateC7H7O4SChemical structure of 4-(hydroxymethyl)benzenesulfonateNot available
Average187.19Da
Monoisotopic187.007053459Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da

Displaying 1–10 of 1580 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total