Escherichia coli strain BIDMC112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain BIDMC112 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 37°C, and typically exhibits a cell arrangement in pairs or singles. BIDMC112 is associated with a wide range of hosts, including Homo sapiens, various domestic animals such as Gallus gallus (chickens), Bos taurus (cattle), and Sus scrofa (pigs), as well as several species of vertebrates and invertebrates. The versatility in its host range suggests a significant ecological adaptability. This strain is notable for its pathogenic potential in humans, being linked to various health issues, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can also cause more severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The diverse array of diseases associated with BIDMC112 highlights its role in both community-acquired and nosocomial infections. In summary, the ecological and pathogenic characteristics of Escherichia coli strain BIDMC112 underscore its significant impact on public health. Its ability to inhabit a variety of hosts and cause a broad spectrum of diseases illustrates the importance of monitoring and understanding this strain in microbiological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain BIDMC112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain BIDMC112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain BIDMC112


Gene Summary

Adenine Count

1283364 bp

Thymine Count

1281198 bp

Guanine Count

1324998 bp

Cytosine Count

1318883 bp

Genome Length

5208446 bp

Protein-coding Genes

4697 genes

Non-Coding Genes

378 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive301889 - 301900Not Available
IntegraseSK85_00276P04890Negative302196 - 30305033185.1
Hypothetical proteinSK85_00277P76516Negative303277 - 30358212133.4
Hypothetical proteinSK85_00278P76515Negative303582 - 30394413672.3
Hypothetical proteinSK85_00279P76514Negative303935 - 30447120272.5
Hypothetical proteinSK85_00280P76513Negative304599 - 30542330488.2
Hypothetical proteinSK85_00281P76512Negative305489 - 30585113088.6
Prophage repressorSK85_00282P18680Negative306554 - 30720123770.4
Putative antirepressor croSK85_00283Not AvailablePositive307344 - 3076049736.61
Transcriptional regulatorSK85_00284P75976Positive307597 - 30815420168.7

Displaying genes 1 – 10 of 5075 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

319 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da

Displaying 1–10 of 319 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total