Escherichia coli strain BIDMC112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain BIDMC112 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 37°C, and typically exhibits a cell arrangement in pairs or singles. BIDMC112 is associated with a wide range of hosts, including Homo sapiens, various domestic animals such as Gallus gallus (chickens), Bos taurus (cattle), and Sus scrofa (pigs), as well as several species of vertebrates and invertebrates. The versatility in its host range suggests a significant ecological adaptability. This strain is notable for its pathogenic potential in humans, being linked to various health issues, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can also cause more severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The diverse array of diseases associated with BIDMC112 highlights its role in both community-acquired and nosocomial infections. In summary, the ecological and pathogenic characteristics of Escherichia coli strain BIDMC112 underscore its significant impact on public health. Its ability to inhabit a variety of hosts and cause a broad spectrum of diseases illustrates the importance of monitoring and understanding this strain in microbiological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain BIDMC112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain BIDMC112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain BIDMC112 aetyz-supercont1.13.C37, whole

Gene Summary

Adenine Count

1283364 bp

Thymine Count

1281198 bp

Guanine Count

1324998 bp

Cytosine Count

1318883 bp

Genome Length

5208446 bp

Protein-coding Genes

4697 genes

Non-Coding Genes

378 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinSK85_02022Not AvailablePositive2051610 - 20517505375.74
hypothetical proteinSK85_02023P64489Negative2051698 - 20518806822.07
leucine efflux proteinSK85_02024A8A0Z3Negative2052053 - 205269123202.0
hth-type transcriptional regulator dmlrSK85_02025P76250Negative2052818 - 205374134606.8
d-malate dehydrogenaseSK85_02026P76251Positive2053844 - 205492940317.2
hypothetical proteinSK85_02027P0ABD2Positive2055135 - 205656552356.5
2fe-2s cluster-containing proteinSK85_02028P0ABR8Positive2056597 - 205772142560.1
oxidoreductaseSK85_02029P76254Positive2057777 - 205874235663.2
ribonuclease dSK85_02030P09155Negative2058796 - 205991142200.0
long-chain-fatty-acid-coa ligaseSK85_02031P69452Negative2059993 - 206174464716.5

Displaying genes 2081 – 2090 of 5075 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total