Enterobacter cloacae subsp. cloacae strain 42324

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae subsp. cloacae strain 42324 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is mesophilic, thriving within moderate temperature ranges. It possesses a single replicon and is surrounded by two membranes, a feature typical of Gram-negative bacteria. E. cloacae strain 42324 is free-living and has been isolated from various habitats, indicating its adaptability to different environments. However, its significance is notably highlighted by its pathogenicity in humans, where it is associated with a range of health effects. This strain has been implicated in conditions such as vertebral osteomyelitis, bacteremia, spondylodiscitis, and various bloodstream infections, including urinary and respiratory tract infections. The ability of E. cloacae strain 42324 to cause infections in humans and other hosts, including Bos (cattle) and Okapia johnstoni (okapi), underscores its role as a potential opportunistic pathogen. This highlights the importance of monitoring such organisms in clinical settings, particularly given their capacity to lead to serious health complications in susceptible individuals. Overall, the ecological insight derived from the pathogenic nature of E. cloacae strain 42324 emphasizes the need for understanding the environmental reservoirs of this bacterium, which could aid in preventing and controlling infections it may cause in human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainsubsp. cloacae strain 42324

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae subsp. cloacae strain 42324
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae subsp. cloacae strain 42324


Gene Summary

Adenine Count

1241248 bp

Thymine Count

1237397 bp

Guanine Count

1477869 bp

Cytosine Count

1483887 bp

Genome Length

5440401 bp

Protein-coding Genes

4951 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gp245SS44_04040P77279Negative879649 - 88032024903.7
proteaseSS44_04045P0AA55Positive880483 - 88139733476.8
membrane proteinSS44_04050P0AAS3Positive881394 - 88184616588.3
transcriptional regulatorSS44_04055Q93CH6Negative881843 - 88225315327.3
AttlNot AvailableNot AvailablePositive882262 - 882281Not Available
IntegraseSS44_04060P36932Negative882340 - 88336238744.9
hypothetical proteinSS44_04065Not AvailablePositive883980 - 88431813174.0
Hypothetical proteinSS44_04070Not AvailablePositive884459 - 8847199781.43
Hypothetical proteinSS44_04075Not AvailablePositive884895 - 8851228688.77
Hypothetical proteinSS44_04080Not AvailablePositive885140 - 88541210911.1

Displaying genes 1 – 10 of 5102 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

311 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002634-(hydroxymethyl)benzenesulfonateC7H7O4SChemical structure of 4-(hydroxymethyl)benzenesulfonateNot available
Average187.19Da
Monoisotopic187.007053459Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da

Displaying 1–10 of 311 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total