Streptococcus oralis subsp. tigurinus strain UC5873

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis subsp. tigurinus strain UC5873 is a Gram-positive, cocci-shaped bacterium that typically exists in pairs or chains. This strain is classified as a facultative anaerobe, meaning it can thrive in both the presence and absence of oxygen. Notably, it has a mesophilic temperature range, which is conducive to growth at moderate temperatures. The strain is characterized by the absence of mobility, as it does not possess flagella. S. oralis subsp. tigurinus strain UC5873 is primarily associated with human hosts and is recognized for its potential pathogenicity. It has been implicated in serious health conditions, including endocarditis, peritonitis, meningitis, and invasive disease. These associations highlight the strain's role in human health, particularly in immunocompromised individuals. The strain is classified as free-living, suggesting that it can exist independently within its host's environment. It contains a single replicon, indicating a streamlined genomic structure that may contribute to its adaptability within host-associated habitats. Understanding the ecological and biological characteristics of S. oralis subsp. tigurinus strain UC5873 is crucial, especially given its implications for human health. The presence of this strain in the human microbiome underscores the importance of monitoring such bacteria, as they can transition from commensal organisms to pathogens under certain conditions, leading to invasive diseases.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainsubsp. tigurinus strain UC5873

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis subsp. tigurinus strain UC5873
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis subsp. tigurinus strain UC5873


Gene Summary

Adenine Count

541157 bp

Thymine Count

538117 bp

Guanine Count

371964 bp

Cytosine Count

384087 bp

Genome Length

1835325 bp

Protein-coding Genes

1796 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hth domain proteinTZ95_00007Not AvailablePositive14944 - 1587036484.0
hypothetical proteinTZ95_00008Not AvailablePositive15955 - 1632314155.6
endo-beta-n-acetylglucosaminidaseTZ95_00009Not AvailableNegative16441 - 21165174305.0
phosphate transporter phouTZ95_00010P54463Positive21500 - 2313159449.5
hypothetical proteinTZ95_00011Not AvailableNegative23226 - 2352211006.5
glutamyl aminopeptidaseTZ95_00012Q48677Negative23544 - 2460838114.4
iron-compound abc transporter permeaseTZ95_00013P94418Positive24845 - 2580435408.5
iron-compound abc transporter permeaseTZ95_00014P94419Positive25794 - 2675036296.2
iron-compound abc transporter atp-binding proteinTZ95_00015P94420Positive26747 - 2749928416.7
iron-compound abc transporter substrate-binding proteinTZ95_00016P11460Positive27597 - 2856834873.5

Displaying genes 11 – 20 of 1859 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

101 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000542HgHgChemical structure of HgNot available
Average200.59Da
Monoisotopic201.9706256Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da

Displaying 1–10 of 101 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total