Escherichia coli strain CVM N33561PS

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CVM N33561PS is a Gram-negative, rod-shaped bacterium that exhibits mobility, facilitated by the presence of flagella. This strain is categorized as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. CVM N33561PS is host-associated and can exist in pairs or singles, showcasing a free-living biotic relationship with a diverse array of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. This strain is associated with a wide range of health effects in humans and animals, primarily manifesting as urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The extensive list of health effects suggests that E. coli CVM N33561PS is a significant pathogen, contributing to serious health challenges, including diarrhea, septicemia, and complications during pregnancy. Given its ability to inhabit multiple hosts and its pathogenic potential, E. coli strain CVM N33561PS plays a crucial role in the ecology of microbial communities associated with both animals and humans. Its presence signifies an intricate relationship between pathogens and their hosts, emphasizing the need for ongoing surveillance and research to better understand its impact on health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CVM N33561PS

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CVM N33561PS
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CVM N33561PS N33561PS_contig_346, whole

Gene Summary

Adenine Count

1390481 bp

Thymine Count

1395869 bp

Guanine Count

1405197 bp

Cytosine Count

1412615 bp

Genome Length

5604162 bp

Protein-coding Genes

5243 genes

Non-Coding Genes

502 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nucleotide excision repair endonucleasePU06_10630Not AvailablePositive2140020 - 214090733726.8
hypothetical proteinPU06_10635Not AvailableNegative2140867 - 214144221578.1
periplasmic proteinPU06_10640Not AvailableNegative2141645 - 214213018172.1
succinylglutamate desuccinylasePU06_10645Not AvailableNegative2142460 - 214342835787.3
succinylarginine dihydrolasePU06_10650Not AvailableNegative2143421 - 214476449254.3
arginine succinyltransferasePU06_10660Not AvailableNegative2146204 - 214723838429.9
acetylornithine aminotransferasePU06_10665Not AvailableNegative2147235 - 214845543667.8
hypothetical proteinPU06_10670Not AvailablePositive2148901 - 214970730970.9
membrane proteinPU06_10675Not AvailablePositive2149874 - 215058426052.6
hypothetical proteinPU06_10680Not AvailablePositive2150589 - 215126624090.6

Displaying genes 2471 – 2480 of 5745 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total