Escherichia coli strain 48

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 48 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is typically found in host-associated habitats, where it can exist in pairs or singles. It thrives optimally at 37 degrees Celsius, fitting within the mesophilic temperature range. E. coli strain 48 is free-living and has a diverse array of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even some plants like Solanum lycopersicum and Brassica oleracea var. italica. This broad host range signifies the strain's ecological versatility and adaptability. The strain is associated with a range of health effects, primarily affecting humans. It is known to contribute to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Its pathogenicity is particularly notable in human health, with implications for both acute and chronic diseases, including renal failure and colorectal cancer. The presence of E. coli strain 48 in various hosts and its potential to cause multiple health issues underscores its significance in microbiology and public health. The strain's ability to thrive in diverse environments and its association with critical health challenges highlight the importance of understanding such organisms in the context of disease prevention and management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 48

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 48
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 48


Gene Summary

Adenine Count

1564116 bp

Thymine Count

1568142 bp

Guanine Count

1598399 bp

Cytosine Count

1592491 bp

Genome Length

6323148 bp

Protein-coding Genes

5133 genes

Non-Coding Genes

757 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinJD73_09125Not AvailablePositive1876728 - 187728221319.1
Derepression proteinJD73_09130Not AvailablePositive1877603 - 18778309031.84
hypothetical proteinJD73_09135Not AvailablePositive1877899 - 187832115777.4
hypothetical proteinJD73_09145Not AvailablePositive1880628 - 18808377532.86
hypothetical proteinJD73_09150Not AvailablePositive1880834 - 188123815331.4
Ren exclusion proteinJD73_09160Not AvailablePositive1881469 - 188178011996.7
Transcriptional regulatorJD73_09165Not AvailableNegative1881846 - 18821099858.98
Phage portal proteinJD73_09170Not AvailableNegative1882147 - 188319939145.8
Terminase, atpaseJD73_09175Not AvailableNegative1883196 - 188500168672.4
Capsid scaffolding proteinJD73_09180Not AvailablePositive1885168 - 188621738099.2

Displaying genes 51 – 60 of 5890 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total