Escherichia coli strain G1/2

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain G1/2 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in varying oxygen conditions. This strain typically arranges itself in pairs or singles and possesses flagella, enabling it to be motile. It is classified as mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary hosts. The strain is host-associated and has been identified in a wide range of organisms, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), Canis lupus familiaris (domestic dogs), and Felis catus (domestic cats), among others. Its biotic relationship is free-living, indicating that it can exist independently in various environments, while also being associated with numerous hosts. E. coli strain G1/2 is known to cause a variety of health issues, particularly in humans, such as urinary tract infections (UTIs), peritonitis, gastrointestinal infections, and neonatal meningitis. Its pathogenicity can lead to severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS), which underscores its role as a significant human pathogen. The strain’s ability to infect multiple hosts highlights its ecological versatility and potential for zoonotic transmission, as it can persist in both human and animal populations, influencing public health and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain G1/2

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain G1/2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain G1/2


Gene Summary

Adenine Count

1254403 bp

Thymine Count

1250435 bp

Guanine Count

1296739 bp

Cytosine Count

1288746 bp

Genome Length

5090326 bp

Protein-coding Genes

4590 genes

Non-Coding Genes

345 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna (cmo5u34)-methyltransferaseEL75_1755Not AvailableNegative1894857 - 189560027792.3
inner membrane protein yecnEL75_1756Not AvailableNegative1895641 - 189603615227.2
putative protein yeceEL75_1757Not AvailableNegative1896089 - 189681427757.3
AttlNot AvailableNot AvailablePositive1896504 - 1896515Not Available
Putative integraseEL75_1758Not AvailableNegative1896841 - 189815449402.3
Hypothetical proteinEL75_1759Not AvailableNegative1898455 - 18986015915.08
Hypothetical proteinEL75_1760Not AvailableNegative1898932 - 189950421233.7
Hypothetical proteinEL75_1761Not AvailableNegative1899506 - 190020125516.4
Hypothetical proteinEL75_1762Not AvailableNegative1900198 - 19004378770.56
Hypothetical proteinEL75_1763Not AvailableNegative1900430 - 19006337960.85

Displaying genes 1 – 10 of 4935 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Neonatal mortalityCausesPMC11597549
Intestinal inflammationCausesPMC12549655
Post-weaning diarrhoeaCausesPMC12943755
BronchopneumoniaCausesPMC6822343
MyositisCausesPMC6822343
FasciitisCausesPMC6822343
Urinary tract infectionCausesPMC7404122
PeritonitisCausesPMC7747055
PeritonitisCausesPMC7953774
SepticemiaCausesPMC9756510

Displaying health effects 51 – 60 of 74 in total