Escherichia coli strain G1/2

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain G1/2 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in varying oxygen conditions. This strain typically arranges itself in pairs or singles and possesses flagella, enabling it to be motile. It is classified as mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary hosts. The strain is host-associated and has been identified in a wide range of organisms, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), Canis lupus familiaris (domestic dogs), and Felis catus (domestic cats), among others. Its biotic relationship is free-living, indicating that it can exist independently in various environments, while also being associated with numerous hosts. E. coli strain G1/2 is known to cause a variety of health issues, particularly in humans, such as urinary tract infections (UTIs), peritonitis, gastrointestinal infections, and neonatal meningitis. Its pathogenicity can lead to severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS), which underscores its role as a significant human pathogen. The strain’s ability to infect multiple hosts highlights its ecological versatility and potential for zoonotic transmission, as it can persist in both human and animal populations, influencing public health and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain G1/2

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain G1/2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain G1/2 EL75_contig_311, whole genome shotgun

Gene Summary

Adenine Count

1254403 bp

Thymine Count

1250435 bp

Guanine Count

1296739 bp

Cytosine Count

1288746 bp

Genome Length

5090326 bp

Protein-coding Genes

4590 genes

Non-Coding Genes

345 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glucans biosynthesis protein cEL75_2697Not AvailablePositive2830900 - 283205744692.9
putative synthaseEL75_2698Not AvailableNegative2832065 - 283354655929.7
hypothetical proteinEL75_2699Not AvailableNegative2833488 - 283402118881.5
putative protein ymdaEL75_2700Not AvailableNegative2834116 - 283442711194.7
curlin, major subunitEL75_2701Not AvailableNegative2834939 - 283539415050.1
transcriptional regulator csgdEL75_2702Not AvailablePositive2836645 - 283729524936.9
curli production assembly component csgeEL75_2703Not AvailablePositive2837300 - 283768914879.6
curli assembly component csgfEL75_2704Not AvailablePositive2837714 - 283813015056.7
curli production componentEL75_2705Not AvailablePositive2838157 - 283899030559.0
hypothetical proteinEL75_2706Not AvailableNegative2839054 - 283957518111.8

Displaying genes 2811 – 2820 of 4935 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total