Mycobacterium abscessus subsp. bolletii strain 369

Mycobacterium abscessus subsp. bolletii strain 369 is a rod-shaped bacterium known for its presence in chloraminated water. It possesses true flagella, indicating motility which may contribute to its ecological adaptability. The strain has a single replicon, which is a characteristic of its genomic structure. This subspecies is notable for its health effects on various hosts, including humans (Homo sapiens), other mammals (Metazoa), birds (Aves), seals (Phocidae), rodents (Rodentia), and big cats (Panthera leo). In humans, M. abscessus subsp. bolletii strain 369 is associated with a wide range of serious health conditions, including endocarditis, peritonitis, and various lung infections such as non-cavitary pneumonia and chronic pulmonary diseases. It can also lead to skin infections and localized lesions, particularly in immunocompromised individuals or those undergoing procedures like peritoneal dialysis, which is linked to PD-associated peritonitis. The diverse range of hosts affected by this bacterium suggests a significant ecological role, as it can thrive in both aquatic environments and within various animal species. The ability to cause disease in multiple hosts indicates its potential for zoonotic transmission, which underscores the importance of monitoring and studying this pathogen in both public health and ecological contexts. Understanding its behavior and impact can aid in developing strategies to mitigate its health risks, particularly in chlorinated water systems where it may proliferate.