Enterobacter cloacae strain e403

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain e403 is a Gram-negative, rod-shaped bacterium that functions as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is characterized by the presence of flagella, indicating potential motility, although it is noted to be non-motile. E. cloacae e403 has a mesophilic temperature range, suggesting optimal growth at moderate temperatures. This bacterium is free-living and can inhabit multiple environments, including human hosts and animals such as Bos (cattle) and Okapia johnstoni (okapi). It is known to be pathogenic to humans, associated with various health complications, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and infections of the bloodstream, urinary, and respiratory tracts. With a single replicon and a double membrane structure, E. cloacae e403 showcases traits typical of many Enterobacteriaceae family members, which often exhibit pathogenic characteristics. The strain’s ability to cause significant health issues in humans underscores its importance in clinical microbiology and public health. The presence of E. cloacae in both human and animal hosts highlights its ecological versatility and potential role in zoonotic transmission. This dual-host affiliation may facilitate its adaptation and persistence in diverse habitats, thereby influencing infection patterns in both humans and animals. Understanding the ecological dynamics of Enterobacter cloacae e403 can provide insights into its epidemiology and impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain e403

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain e403
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain e403 genome assembly, contig:

Gene Summary

Adenine Count

2084158 bp

Thymine Count

2080374 bp

Guanine Count

3377896 bp

Cytosine Count

3393559 bp

Genome Length

11583497 bp

Protein-coding Genes

10350 genes

Non-Coding Genes

329 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetate operon repressorSAMEA2273162_00392Not AvailableNegative402606 - 40334326950.1
regulator of ribonuclease activitySAMEA2273162_00393Not AvailablePositive403513 - 40420523914.0
d-3-phosphoglycerate dehydrogenaseSAMEA2273162_00394Not AvailablePositive404205 - 40514933270.1
copper-binding protein pcoeSAMEA2273162_00395Not AvailableNegative405518 - 40579310114.8
two-component system%2c ompr family%2c heavy metal sensor histidine kinase cussSAMEA2273162_00396Not AvailableNegative406170 - 40757053079.8
two component heavy metal response transcriptional regulatorSAMEA2273162_00397Not AvailableNegative407567 - 40824725677.1
copper resistance protein dSAMEA2273162_00398Not AvailableNegative408302 - 40923133850.4
uncharacterized protein involved in copper resistanceSAMEA2273162_00399Not AvailableNegative409656 - 41055233200.0
copper-resistance protein%2c copa familySAMEA2273162_00400Not AvailableNegative410552 - 41236967242.4
copper-translocating p-type atpaseSAMEA2273162_00401Not AvailableNegative414390 - 41683787062.6

Displaying genes 641 – 650 of 10679 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total