Enterobacter cloacae strain e1252

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain e1252 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic characteristics, allowing it to thrive in both aerobic and anaerobic environments. This strain is classified as mesophilic, indicating its optimal growth temperature aligns with moderate temperature ranges. E. cloacae strain e1252 has a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. This strain is non-motile despite possessing flagella, suggesting that it may rely on other mechanisms for colonization and persistence in its environments. E. cloacae strain e1252 is free-living, meaning it does not have a specific symbiotic relationship with a host organism, although it has been associated with several hosts, including Homo sapiens, Bos, and Okapia johnstoni. Pathogenically, E. cloacae strain e1252 has been implicated in various health conditions in humans, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and urinary and respiratory tract infections. These health effects highlight the strain's potential to cause serious bloodstream infections (BSI) and related complications in humans. The ecological insight provided by the versatility of Enterobacter cloacae strain e1252, coupled with its potential pathogenicity in humans and other hosts, underscores the importance of monitoring this bacterium in clinical and environmental contexts. Its ability to adapt to different habitats and the associated health risks it presents emphasize its relevance in both microbiological research and public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain e1252

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain e1252
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain e1252 genome assembly, contig:

Gene Summary

Adenine Count

1133685 bp

Thymine Count

1140209 bp

Guanine Count

1421070 bp

Cytosine Count

1420123 bp

Genome Length

5121988 bp

Protein-coding Genes

4576 genes

Non-Coding Genes

333 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
long polar fimbria protein aSAMEA2273318_00617P75860Positive655606 - 65614217981.1
p pilus assembly protein%2c chaperone papdSAMEA2273318_00618Q8X5K6Positive656211 - 65688524703.5
outer membrane usher protein lpfcSAMEA2273318_00619Not AvailablePositive656913 - 65949293760.6
p pilus assembly protein%2c pilin fimaSAMEA2273318_00620Not AvailablePositive659479 - 66046834693.2
p pilus assembly protein%2c pilin fimaSAMEA2273318_00621Not AvailablePositive660474 - 66097717803.1
atp-dependent dna helicase dingSAMEA2273318_00622Q8X7X9Negative660964 - 66314181824.2
atp-dependent rna helicase rhleSAMEA2273318_00623P25888Negative663239 - 66462450784.1
transcriptional regulator tetrSAMEA2273318_00624P0ACU0Positive664832 - 66550924984.9
putative hlyd family secretion proteinSAMEA2273318_00625A4W8D7Positive665506 - 66650136110.9
abc transporterSAMEA2273318_00626P0A9U1Positive666494 - 66823363652.0

Displaying genes 901 – 910 of 4909 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

295 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000433malonateC3H2O4Chemical structure of malonateNot available
Average102.0456Da
Monoisotopic101.9953086Da

Displaying 1–10 of 295 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total