Enterobacter cloacae strain e1252

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain e1252 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic characteristics, allowing it to thrive in both aerobic and anaerobic environments. This strain is classified as mesophilic, indicating its optimal growth temperature aligns with moderate temperature ranges. E. cloacae strain e1252 has a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. This strain is non-motile despite possessing flagella, suggesting that it may rely on other mechanisms for colonization and persistence in its environments. E. cloacae strain e1252 is free-living, meaning it does not have a specific symbiotic relationship with a host organism, although it has been associated with several hosts, including Homo sapiens, Bos, and Okapia johnstoni. Pathogenically, E. cloacae strain e1252 has been implicated in various health conditions in humans, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and urinary and respiratory tract infections. These health effects highlight the strain's potential to cause serious bloodstream infections (BSI) and related complications in humans. The ecological insight provided by the versatility of Enterobacter cloacae strain e1252, coupled with its potential pathogenicity in humans and other hosts, underscores the importance of monitoring this bacterium in clinical and environmental contexts. Its ability to adapt to different habitats and the associated health risks it presents emphasize its relevance in both microbiological research and public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain e1252

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain e1252
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain e1252 genome assembly, contig:

Gene Summary

Adenine Count

1133685 bp

Thymine Count

1140209 bp

Guanine Count

1421070 bp

Cytosine Count

1420123 bp

Genome Length

5121988 bp

Protein-coding Genes

4576 genes

Non-Coding Genes

333 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
arsenical pump-driving atpaseSAMEA2273318_04967Not AvailableNegative5068845 - 507059663385.0
arsenical resistance operon trans-acting repressor arsdSAMEA2273318_04968P52148Negative5070614 - 507097612943.8
arsr family transcriptional regulatorSAMEA2273318_04969Not AvailableNegative5071024 - 507137713000.0
ferritin-like proteinSAMEA2273318_04970P0A9A4Negative5072149 - 507264919032.6
transposaseSAMEA2273318_04971Not AvailableNegative5073085 - 50733279448.32
uncharacterised proteinSAMEA2273318_04972Not AvailableNegative5074114 - 50743538815.81
regulatory protein tetrSAMEA2273318_04973Not AvailableNegative5074495 - 507511223732.0
inner membrane component of tripartite multidrug resistance systemSAMEA2273318_04974Q83P86Positive5075548 - 507634230263.1
homoprotocatechuate degradation operon regulator%2c hparSAMEA2273318_04975Not AvailablePositive5076704 - 507714116665.5
putative cytoplasmic proteinSAMEA2273318_04976Q0TBK7Negative5077145 - 50773457791.38

Displaying genes 4851 – 4860 of 4909 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

295 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000433malonateC3H2O4Chemical structure of malonateNot available
Average102.0456Da
Monoisotopic101.9953086Da

Displaying 1–10 of 295 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total