Streptococcus suis strain LSS49

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus suis strain LSS49 is a Gram-positive bacterium characterized by its cocci shape, which typically forms chains, pairs, or singles. This strain is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, indicating its mesophilic nature. S. suis LSS49 does not exhibit mobility and possesses a single membrane and one replicon. This bacterium is known to have a free-living biotic relationship and can be isolated from various hosts, including Homo sapiens (humans), Metazoa, Danio rerio (zebrafish), and Sus scrofa (domestic pigs). Its presence in these diverse hosts highlights its ecological versatility and potential zoonotic implications. Health effects associated with S. suis strain LSS49 are significant, as it has been implicated in various serious conditions, including endocarditis, meningitis, septicaemia, endophthalmitis, sepsis, arthritis, purulent meningitis, cerebral ischemia, and streptococcal diseases. These health impacts underscore the clinical importance of this strain, particularly in humans, where it can lead to severe infections and systemic disease. Given its ability to inhabit specialized niches within multiple hosts and its association with a range of pathogenic outcomes, S. suis strain LSS49 serves as an important subject of study in understanding both microbial ecology and the epidemiology of streptococcal infections. The strain's diverse host range and pathogenic potential illustrate the complex interactions between bacteria and their hosts in various ecological settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus suis
Strainstrain LSS49

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus suis strain LSS49
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Danio rerio
Cell arrangementChains - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus suis strain LSS49


Gene Summary

Adenine Count

658921 bp

Thymine Count

654856 bp

Guanine Count

452262 bp

Cytosine Count

469025 bp

Genome Length

2235066 bp

Protein-coding Genes

2087 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
orotidine 5'-phosphate decarboxylaseERS132411_00373A4W1D9Negative398170 - 39886525364.5
dihydroorotate dehydrogenase 1bERS132411_00375Q8DQ37Negative399030 - 39997133266.6
dihydroorotate dehydrogenase electron transfer subunitERS132411_00376Q8DQ38Negative399981 - 40075428253.5
transcriptional regulatorERS132411_00378P70785Positive400969 - 40188035283.3
adp-glucose pyrophosphorylaseERS132411_00379A6M331Positive402044 - 40317141409.4
adp-glucose pyrophosphorylaseERS132411_00380O08327Positive403184 - 40429942084.2
glycogen synthaseERS132411_00381A3CM04Positive404308 - 40575355570.0
1%2c4-alpha-glucan branching enzymeERS132411_00382P30537Positive405826 - 40766472547.0
amino acid abc transporter periplasmic proteinERS132411_00383P54535Negative407791 - 40859128015.3
amino acid abc transporter amino acid-binding proteinERS132411_00384P0AEQ5Negative408762 - 40957129180.6

Displaying genes 371 – 380 of 2129 in total

Metabolites

107 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00008001,8-diazacyclotetradecane-2,9-dioneC12H22N2O2Chemical structure of 1,8-diazacyclotetradecane-2,9-dioneNot available
Average226.32Da
Monoisotopic226.168127956Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da

Displaying 1–10 of 107 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC11046750
EndocarditisCausesPMC11046750
ArthritisCausesPMC11046750
SepsisCausesPMC11046750
Purulent meningitisCausesPMC11046750
Cerebral ischemiaCausesPMC11046750
Streptococcal diseaseCausesPMC11542422
MeningitisCausesPMC11542422
SepticemiaCausesPMC11542422
EndocarditisCausesPMC11542422

Displaying health effects 1 – 10 of 49 in total