Streptococcus pneumoniae strain 2245STDY5699081

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain 2245STDY5699081 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape and tendency to form chains or pairs. This strain is non-motile and lacks flagella, which influences its mode of colonization and infection. It thrives optimally at a temperature of 30°C, placing it within the mesophilic range, and is known to inhabit multiple environments, including those associated with various hosts. This strain primarily affects Homo sapiens but has also been identified in other hosts, such as Gallus gallus (chickens), Cavia (guinea pigs), Meriones unguiculatus (gerbils), and Chinchilla. Its pathogenicity in humans is significant, as it is associated with a range of serious health conditions, including bacteremia, pneumonia, meningitis, sepsis, and various forms of respiratory and ear infections. Strain 2245STDY5699081 is notably linked to community-acquired pneumonia (CAP) and invasive pneumococcal disease (IPD), which can lead to severe complications in vulnerable populations. The presence of this bacterium in multiple hosts suggests a complex ecological role, potentially aiding in the understanding of zoonotic transmission and the dynamics of infectious disease spread. The diverse health impacts underscore the importance of monitoring this strain in clinical settings, particularly given its ability to cause invasive diseases in humans. As a free-living organism, its adaptation to various environments may contribute to its persistence and pathogenic potential across different ecosystems.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain 2245STDY5699081

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain 2245STDY5699081
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain 2245STDY5699081


Gene Summary

Adenine Count

633601 bp

Thymine Count

640329 bp

Guanine Count

417778 bp

Cytosine Count

416253 bp

Genome Length

2109850 bp

Protein-coding Genes

2001 genes

Non-Coding Genes

137 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-n-acetylmuramate-alanine ligaseSAMEA2335988_00024Not AvailableNegative19666 - 2100049876.7
atp-binding proteinSAMEA2335988_00025Not AvailableNegative21011 - 2162823845.3
putative snf-family helicaseSAMEA2335988_00026Not AvailableNegative21676 - 24774118183.0
maly, bifunctional plp-dependent enzymeSAMEA2335988_00027Not AvailableNegative24867 - 2603344410.0
cystathionine gamma-synthaseSAMEA2335988_00028Not AvailableNegative26041 - 2713540105.6
abc transporter atp-binding proteinSAMEA2335988_00029Not AvailableNegative27293 - 2897562660.5
oligopeptide binding lipoproteinSAMEA2335988_00030Not AvailableNegative29147 - 3110572575.5
polysaccharide biosynthesis proteinSAMEA2335988_00031Not AvailableNegative31309 - 3293160106.5
udp-n-acetylmuramyl tripeptide synthase mureSAMEA2335988_00032Not AvailablePositive33037 - 3448253819.2
csbd-like proteinSAMEA2335988_00033Not AvailableNegative34528 - 347226638.86

Displaying genes 151 – 160 of 2138 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total