Streptococcus pneumoniae strain 2245STDY5699081

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain 2245STDY5699081 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape and tendency to form chains or pairs. This strain is non-motile and lacks flagella, which influences its mode of colonization and infection. It thrives optimally at a temperature of 30°C, placing it within the mesophilic range, and is known to inhabit multiple environments, including those associated with various hosts. This strain primarily affects Homo sapiens but has also been identified in other hosts, such as Gallus gallus (chickens), Cavia (guinea pigs), Meriones unguiculatus (gerbils), and Chinchilla. Its pathogenicity in humans is significant, as it is associated with a range of serious health conditions, including bacteremia, pneumonia, meningitis, sepsis, and various forms of respiratory and ear infections. Strain 2245STDY5699081 is notably linked to community-acquired pneumonia (CAP) and invasive pneumococcal disease (IPD), which can lead to severe complications in vulnerable populations. The presence of this bacterium in multiple hosts suggests a complex ecological role, potentially aiding in the understanding of zoonotic transmission and the dynamics of infectious disease spread. The diverse health impacts underscore the importance of monitoring this strain in clinical settings, particularly given its ability to cause invasive diseases in humans. As a free-living organism, its adaptation to various environments may contribute to its persistence and pathogenic potential across different ecosystems.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain 2245STDY5699081

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain 2245STDY5699081
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain 2245STDY5699081


Gene Summary

Adenine Count

633601 bp

Thymine Count

640329 bp

Guanine Count

417778 bp

Cytosine Count

416253 bp

Genome Length

2109850 bp

Protein-coding Genes

2001 genes

Non-Coding Genes

137 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hydroxyethylthiazole kinaseSAMEA2335988_00952Not AvailableNegative914655 - 91545829083.2
thiw superfamily proteinSAMEA2335988_00953Not AvailableNegative915458 - 91598219190.3
transcriptional activator tena, tena/thi-4 family proteinSAMEA2335988_00954Not AvailableNegative915987 - 91667927372.5
cobalt abc transporter domain-containing proteinSAMEA2335988_00955Not AvailableNegative916690 - 91734024976.6
cobalt or other cation abc transporter atp-binding proteinSAMEA2335988_00956Not AvailableNegative917342 - 91872752285.8
cobalt abc transporter permeaseSAMEA2335988_00957Not AvailableNegative918728 - 91928820310.4
thiamine-phosphate pyrophosphorylaseSAMEA2335988_00959Not AvailableNegative919847 - 92047623262.3
hydroxyethylthiazole kinaseSAMEA2335988_00960Not AvailableNegative920478 - 92126027666.6
chlorohydrolaseSAMEA2335988_00961Not AvailablePositive921363 - 9215908745.52
transcriptional regulator, tena/thi-4 family proteinSAMEA2335988_00962Not AvailableNegative921587 - 92225525615.5

Displaying genes 991 – 1000 of 2138 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total