Streptococcus pneumoniae strain GPSC47

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain GPSC47 is a Gram-positive, cocci-shaped bacterium that typically arranges itself in chains or pairs. It is a facultative anaerobe, capable of thriving in varying oxygen levels, and is classified as mesophilic, with an optimal growth temperature of 30°C. This strain is non-motile and lacks flagella, indicating that it does not have the means for active movement. S. pneumoniae GPSC47 is free-living and has been identified in multiple habitats, primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Cavia (guinea pigs), Meriones unguiculatus (gerbils), and Chinchilla. The strain is known for its pathogenicity in humans, causing a range of serious health effects, including bacteremia, pneumonia, meningitis, and various forms of otitis media. It is also responsible for invasive pneumococcal disease (IPD) and can lead to conditions such as septicemia and acute respiratory infections. The strain possesses four replicons and features a single membrane structure, typical of many Gram-positive bacteria. Given its ability to infect multiple hosts and cause significant health issues, S. pneumoniae GPSC47 highlights the ecological complexity of microbial interactions in both human and animal populations. Its prevalence in the community and capacity to cause severe infections underline the importance of ongoing surveillance and research into its pathogenic mechanisms and potential treatments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain GPSC47

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain GPSC47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain GPSC47 genome assembly, contig:

Gene Summary

Adenine Count

675444 bp

Thymine Count

678377 bp

Guanine Count

442729 bp

Cytosine Count

436805 bp

Genome Length

2233755 bp

Protein-coding Genes

2131 genes

Non-Coding Genes

171 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamine amidotransferase, class iSAMEA104154734_01609Not AvailablePositive1568549 - 156923825813.8
dna repair protein radcSAMEA104154734_01610Not AvailableNegative1569235 - 156991525537.1
atp-dependent dna helicase pcraSAMEA104154734_01611Not AvailableNegative1569958 - 157224985979.3
transposaseSAMEA104154734_01612Not AvailableNegative1572440 - 157275411937.8
transposase-like protein, is1381 isspn7SAMEA104154734_01613Not AvailableNegative1572827 - 157322515181.2
degenerate transposase (orf1)SAMEA104154734_01614Not AvailableNegative1573233 - 157350510473.3
methionyl aminopeptidaseSAMEA104154734_01615Not AvailableNegative1573604 - 157446431651.9
drtgg domain/cbs domain-containing proteinSAMEA104154734_01616Not AvailableNegative1574480 - 157575747652.8
acetyltransferaseSAMEA104154734_01617Not AvailableNegative1575750 - 157630121764.0
udp-n-acetylglucosamine 1-carboxyvinyltransferase 2SAMEA104154734_01618Not AvailableNegative1576317 - 157757645027.6

Displaying genes 8741 – 8750 of 9374 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total