Streptococcus pneumoniae strain GPSC47

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain GPSC47 is a Gram-positive, cocci-shaped bacterium that typically arranges itself in chains or pairs. It is a facultative anaerobe, capable of thriving in varying oxygen levels, and is classified as mesophilic, with an optimal growth temperature of 30°C. This strain is non-motile and lacks flagella, indicating that it does not have the means for active movement. S. pneumoniae GPSC47 is free-living and has been identified in multiple habitats, primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Cavia (guinea pigs), Meriones unguiculatus (gerbils), and Chinchilla. The strain is known for its pathogenicity in humans, causing a range of serious health effects, including bacteremia, pneumonia, meningitis, and various forms of otitis media. It is also responsible for invasive pneumococcal disease (IPD) and can lead to conditions such as septicemia and acute respiratory infections. The strain possesses four replicons and features a single membrane structure, typical of many Gram-positive bacteria. Given its ability to infect multiple hosts and cause significant health issues, S. pneumoniae GPSC47 highlights the ecological complexity of microbial interactions in both human and animal populations. Its prevalence in the community and capacity to cause severe infections underline the importance of ongoing surveillance and research into its pathogenic mechanisms and potential treatments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain GPSC47

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain GPSC47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain GPSC47 genome assembly, contig:

Gene Summary

Adenine Count

675444 bp

Thymine Count

678377 bp

Guanine Count

442729 bp

Cytosine Count

436805 bp

Genome Length

2233755 bp

Protein-coding Genes

2131 genes

Non-Coding Genes

171 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
voltage-gated chloride channel family proteinSAMEA104038592_01030Not AvailablePositive1002504 - 100405456476.7
tyrosine recombinaseSAMEA104038592_01031Not AvailablePositive1004548 - 100561841145.5
lipoate protein ligase aSAMEA104038592_01032Not AvailableNegative1005691 - 100668037706.9
dihydrolipoyl dehydrogenaseSAMEA104038592_01033Not AvailableNegative1006744 - 100844760358.4
dihydrolipoamide acetyltransferaseSAMEA104038592_01034Not AvailableNegative1008493 - 100953638100.8
putative acetoin dehydrogenaseSAMEA104038592_01035Not AvailableNegative1009754 - 101074635824.1
acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alphaSAMEA104038592_01036Not AvailableNegative1010762 - 101173035112.0
mate efflux family proteinSAMEA104038592_01037Not AvailableNegative1011884 - 101324550075.6
uncharacterised proteinSAMEA104038592_01038Not AvailableNegative1013256 - 10135169972.8
dihydroorotaseSAMEA104038592_01039Not AvailableNegative1013530 - 101479845330.4

Displaying genes 5841 – 5850 of 9374 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total