Gardnerella vaginalis JCP8151B

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis JCP8151B is a Gram-positive, rod-shaped bacterium that exhibits anaerobic respiration and is classified as a chemoheterotroph. This organism is non-motile and does not possess flagella, indicating a lack of mobility. It is typically found in a host-associated habitat, primarily colonizing Homo sapiens, where it plays a role in human health. The optimal growth temperature for Gardnerella vaginalis JCP8151B is 37°C, which falls within the mesophilic temperature range. The bacterium has a single replicon and one membrane, characteristics that are common among certain bacterial species. As a free-living organism, it has the potential to exist independently, although its primary association with humans suggests a more complex interaction. G. vaginalis is notably linked to bacterial vaginosis (BV), a common condition that can affect women's reproductive health. This association highlights the importance of understanding the ecological role of G. vaginalis in the vaginal microbiome. Despite being a part of the normal flora in some individuals, an overgrowth can disrupt the balance of microbial communities and lead to health complications. In conclusion, Gardnerella vaginalis JCP8151B presents significant implications for human health, particularly regarding its role in bacterial vaginosis. Understanding its traits and behaviors can aid in comprehending its impact on the vaginal microbiome and overall female health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainJCP8151B

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis JCP8151B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Gardnerella vaginalis JCP8151B


Gene Summary

Adenine Count

445745 bp

Thymine Count

450545 bp

Guanine Count

335843 bp

Cytosine Count

319104 bp

Genome Length

1551237 bp

Protein-coding Genes

1450 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cobalt transport proteinHMPREF1583_00014Not AvailableNegative22714 - 2340925443.4
cobalt abc transporter, atp-binding proteinHMPREF1583_00015Not AvailableNegative23610 - 2519957670.1
hypothetical proteinHMPREF1583_00016Not AvailableNegative25399 - 2600121137.0
Trna-proNot AvailableNot AvailablePositive26259 - 26332Not Available
hypothetical proteinHMPREF1583_00018Not AvailablePositive26468 - 2752038149.4
glycogen debranching enzyme glgxHMPREF1583_00019Not AvailableNegative27645 - 2976880766.5
tigr00252 family proteinHMPREF1583_00020Not AvailablePositive29993 - 3047518881.0
mg chelatase-like proteinHMPREF1583_00021Not AvailablePositive30475 - 3216061085.2
dna protecting protein dpraHMPREF1583_00022Not AvailablePositive32157 - 3368355573.3
succinate dehydrogenase or fumarate reductase, flavoprotein subunitHMPREF1583_00023Not AvailablePositive33774 - 3571771333.9

Displaying genes 31 – 40 of 1506 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

11 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0003686(2E,6E,10E)-geranylgeranyl diphosphateC20H33O7P2Chemical structure of (2E,6E,10E)-geranylgeranyl diphosphateNot available
Average447.426Da
Monoisotopic447.171798138Da
BASm0003701L-methionine (S)-S-oxideC5H11NO3SChemical structure of L-methionine (S)-S-oxide62697-73-8
Average165.21Da
Monoisotopic165.045964392Da
BASm0004122ADP-L-glycero-beta-D-manno-heptoseC17H25N5O16P2Chemical structure of ADP-L-glycero-beta-D-manno-heptoseNot available
Average617.355Da
Monoisotopic617.078250901Da
BASm0004394zeaxanthin bis(beta-D-glucoside)C52H76O12Chemical structure of zeaxanthin bis(beta-D-glucoside)Not available
Average893.168Da
Monoisotopic892.5336779Da
BASm00068103-(methylsulfanyl)propanoyl-CoAC25H38N7O17P3S2Chemical structure of 3-(methylsulfanyl)propanoyl-CoANot available
Average865.65Da
Monoisotopic865.1000405Da
BASm00072473-(methylsulfanyl)acryloyl-CoAC25H36N7O17P3S2Chemical structure of 3-(methylsulfanyl)acryloyl-CoANot available
Average863.64Da
Monoisotopic863.0843904Da
BASm0008659propionate 3-nitronateC3H4NO4Chemical structure of propionate 3-nitronateNot available
Average118.069Da
Monoisotopic118.0145812Da
BASm0010884(7R,8S)-7,8-diammoniononanoateC9H21N2O2Chemical structure of (7R,8S)-7,8-diammoniononanoateNot available
Average189.278Da
Monoisotopic189.1597543Da

Displaying 1–10 of 11 metabolites

Health Effects

Health ConditionRelationReference
BvCausesPMC12800088

Displaying health effects 1 – 1 of 1 in total