Helicobacter pylori Hp P-23

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-23 is a microaerophilic, Gram-negative bacterium characterized by its spiral shape (spirilla) and presence of flagella. It is typically found in a host-associated habitat, where it exists as a free-living organism. Hp P-23 has a singular cell arrangement, appearing as singles rather than clusters or chains. The bacterium is mesophilic, with an optimal growth temperature of 37°C, which aligns with the typical temperature of the human stomach, its primary habitat. Hp P-23 is notable for having two membranes and a single replicon, which is common in many Gram-negative bacteria. The presence of flagella contributes to its motility, although it does not exhibit mobility in the traditional sense, indicating a more complex interaction with its environment. Understanding the characteristics of Helicobacter pylori Hp P-23 is crucial, as it is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. Its specialized adaptations, such as microaerophilic growth requirements and optimal temperature, suggest a highly evolved relationship with its gastric environment. This relationship underscores the bacterium's role in the human microbiome and its potential implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-23

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-23
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-23 HpP_23.contig.2_1, whole genome

Gene Summary

Adenine Count

503121 bp

Thymine Count

502536 bp

Guanine Count

325090 bp

Cytosine Count

312778 bp

Genome Length

1643525 bp

Protein-coding Genes

1683 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein grpeHPHPP23_0263B5Z9P1Negative243095 - 24367022112.3
heat-inducible transcription repressor hrcaHPHPP23_0264O24933Negative243670 - 24450032053.6
l-fuculose-1-phosphate aldolaseHPHPP23_0265Not AvailablePositive244786 - 24534922080.4
hypothetical proteinHPHPP23_0266Not AvailablePositive245370 - 24566611057.5
motility accessory factorHPHPP23_0267Not AvailableNegative245678 - 24756172149.4
flagellin bHPHPP23_0268Q9ZMV8Negative247622 - 24916653915.3
dna topoisomerase iHPHPP23_0269Not AvailablePositive249332 - 25154283079.2
radical sam domain-containing proteinHPHPP23_0270P56080Positive251535 - 25246134307.1
hypothetical proteinHPHPP23_0271Not AvailableNegative252600 - 2527706475.03
hypothetical proteinHPHPP23_0272Not AvailablePositive252926 - 25324312340.9

Displaying genes 281 – 290 of 1739 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.