Helicobacter pylori Hp H-28

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-28 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism is notable for its possession of flagella, which aids in its movement, although it is classified as non-motile in a practical sense due to its specific ecological interactions. H. pylori Hp H-28 thrives optimally at 37°C, falling within the mesophilic temperature range, which aligns with its habitat as a host-associated organism. The bacterium has a unique cellular structure, featuring two membranes and a single replicon, indicating a relatively simple genomic organization. H. pylori is known for its free-living biotic relationship, suggesting that it can exist independently within its ecological niche, although it is often associated with human hosts where it can influence gastric health. The presence of H. pylori in the human stomach is significant due to its role in various gastric disorders, including gastritis and peptic ulcers. Understanding the specific traits of H. pylori Hp H-28 can provide insights into its ecological dynamics within the human microbiome and its potential impacts on human health. Its microaerophilic nature and optimal growth conditions reflect its adaptation to the unique environment of the stomach, where oxygen levels are limited. This bacterium's ability to thrive in such conditions underscores the complexity of host-associated microbial ecosystems and their influence on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-28

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-28
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-28 HpH_28.contig.15_1, whole genome

Gene Summary

Adenine Count

493356 bp

Thymine Count

498031 bp

Guanine Count

313316 bp

Cytosine Count

320297 bp

Genome Length

1625000 bp

Protein-coding Genes

1623 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipopolysaccharide transport periplasmic protein lptaHPHPH28_0058Not AvailableNegative54395 - 5495220900.2
hypothetical proteinHPHPH28_0059Not AvailableNegative54952 - 5554522822.1
3-deoxy-d-manno-octulosonate 8-phosphate phosphataseHPHPH28_0060Not AvailableNegative55520 - 5600217783.8
rlpa-like lipoproteinHPHPH28_0061Not AvailableNegative56011 - 5695835540.3
5s ribosomal rnaNot AvailableNot AvailablePositive57018 - 57133Not Available
membrane-bound lytic murein transglycosylase dHPHPH28_0062Not AvailableNegative56958 - 5807043078.7
mg-dependent dnaseHPHPH28_0063Not AvailableNegative58165 - 5892929151.9
riboflavin synthase, alpha subunitHPHPH28_0064Not AvailablePositive59006 - 5962622827.4
putative flagellar biosynthesis proteinHPHPH28_0065Not AvailablePositive59627 - 598999924.03
d-methionine transport system atp-binding proteinHPHPH28_0066Not AvailablePositive59921 - 6090436594.0

Displaying genes 61 – 70 of 1669 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.