Helicobacter pylori Hp H-28

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-28 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism is notable for its possession of flagella, which aids in its movement, although it is classified as non-motile in a practical sense due to its specific ecological interactions. H. pylori Hp H-28 thrives optimally at 37°C, falling within the mesophilic temperature range, which aligns with its habitat as a host-associated organism. The bacterium has a unique cellular structure, featuring two membranes and a single replicon, indicating a relatively simple genomic organization. H. pylori is known for its free-living biotic relationship, suggesting that it can exist independently within its ecological niche, although it is often associated with human hosts where it can influence gastric health. The presence of H. pylori in the human stomach is significant due to its role in various gastric disorders, including gastritis and peptic ulcers. Understanding the specific traits of H. pylori Hp H-28 can provide insights into its ecological dynamics within the human microbiome and its potential impacts on human health. Its microaerophilic nature and optimal growth conditions reflect its adaptation to the unique environment of the stomach, where oxygen levels are limited. This bacterium's ability to thrive in such conditions underscores the complexity of host-associated microbial ecosystems and their influence on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-28

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-28
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-28 HpH_28.contig.15_1, whole genome

Gene Summary

Adenine Count

493356 bp

Thymine Count

498031 bp

Guanine Count

313316 bp

Cytosine Count

320297 bp

Genome Length

1625000 bp

Protein-coding Genes

1623 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
riboflavin biosynthesis protein ribdHPHPH28_1633Not AvailableNegative1576134 - 157716839065.5
sodium/glutamate symporterHPHPH28_1634Not AvailableNegative1577165 - 157839143930.1
saccharopine dehydrogenaseHPHPH28_1635Not AvailablePositive1578534 - 157967643353.2
cytochrome c oxidase accessory protein ccogHPHPH28_1636Not AvailableNegative1579686 - 158106252691.1
acyl-phosphate glycerol 3-phosphate acyltransferaseHPHPH28_1637Not AvailablePositive1581168 - 158183023805.3
dihydroneopterin aldolaseHPHPH28_1638Not AvailablePositive1581827 - 158218013646.8
iron-regulated outer membrane protein frpb4HPHPH28_1639Not AvailablePositive1582164 - 158249012580.3
putative iron-regulated outer membrane proteinHPHPH28_1640Not AvailablePositive1582667 - 158523494888.0
l-seryl-trna(sec) selenium transferaseHPHPH28_1641Not AvailablePositive1585463 - 158662343937.5
transcription elongation protein nusaHPHPH28_1642Not AvailablePositive1586725 - 158791244737.5

Displaying genes 1631 – 1640 of 1669 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.