Helicobacter pylori Hp H-28

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-28 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism is notable for its possession of flagella, which aids in its movement, although it is classified as non-motile in a practical sense due to its specific ecological interactions. H. pylori Hp H-28 thrives optimally at 37°C, falling within the mesophilic temperature range, which aligns with its habitat as a host-associated organism. The bacterium has a unique cellular structure, featuring two membranes and a single replicon, indicating a relatively simple genomic organization. H. pylori is known for its free-living biotic relationship, suggesting that it can exist independently within its ecological niche, although it is often associated with human hosts where it can influence gastric health. The presence of H. pylori in the human stomach is significant due to its role in various gastric disorders, including gastritis and peptic ulcers. Understanding the specific traits of H. pylori Hp H-28 can provide insights into its ecological dynamics within the human microbiome and its potential impacts on human health. Its microaerophilic nature and optimal growth conditions reflect its adaptation to the unique environment of the stomach, where oxygen levels are limited. This bacterium's ability to thrive in such conditions underscores the complexity of host-associated microbial ecosystems and their influence on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-28

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-28
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-28 HpH_28.contig.15_1, whole genome

Gene Summary

Adenine Count

493356 bp

Thymine Count

498031 bp

Guanine Count

313316 bp

Cytosine Count

320297 bp

Genome Length

1625000 bp

Protein-coding Genes

1623 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl-coa carboxylase, biotin carboxylase subunitHPHPH28_1353Not AvailablePositive1333713 - 133508050600.2
putative type ii dna modification enzymeHPHPH28_1354Not AvailablePositive1335173 - 133613537441.9
type ii restriction endonucleaseHPHPH28_1355Not AvailablePositive1336135 - 133668321413.9
hypothetical proteinHPHPH28_1356Not AvailablePositive1336777 - 133737622980.9
udp-4-keto-6-deoxy-n-acetylglucosamine 4-aminotransferaseHPHPH28_1357Not AvailablePositive1337373 - 133850042251.1
Trna-leuNot AvailableNot AvailablePositive1338537 - 1338621Not Available
ribonucleoside-diphosphate reductase subunit betaHPHPH28_1359Not AvailablePositive1338821 - 133984639514.1
protein-l-isoaspartate o-methyltransferaseHPHPH28_1360Not AvailablePositive1339856 - 134048523897.1
hypothetical proteinHPHPH28_1361Not AvailablePositive1340496 - 134153339676.0
trna pseudouridine synthase aHPHPH28_1362Not AvailablePositive1341534 - 134226227304.4

Displaying genes 1351 – 1360 of 1669 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.