Helicobacter pylori Hp A-9

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp A-9 is a Gram-negative bacterium that belongs to the class of spirilla. It exhibits a microaerophilic oxygen requirement, indicating that it thrives in environments with low oxygen levels. This organism is characterized by its single-cell arrangement and is equipped with flagella, which supports its mobility, although it is noted that it does not actively exhibit mobility behavior. H. pylori Hp A-9 is typically found in host-associated habitats, suggesting a symbiotic relationship with its host. The bacterium is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, further emphasizing its association with human hosts. It possesses a unique cellular structure with two membranes and a single replicon, which are characteristic traits of its Gram-negative classification. The biological and ecological implications of H. pylori Hp A-9's traits highlight its role in the human microbiome. Given its free-living nature within host environments, it suggests that this bacterium may play a significant role in maintaining gastrointestinal health or influencing pathogenic conditions, such as peptic ulcers and gastric cancer, which are associated with H. pylori infections. Understanding the specific traits of H. pylori Hp A-9 aids in elucidating its interactions within host organisms and its broader ecological impacts.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-9

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-9
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-9 HpA_9.contig.17_1, whole genome shotgun

Gene Summary

Adenine Count

519991 bp

Thymine Count

534023 bp

Guanine Count

330631 bp

Cytosine Count

335762 bp

Genome Length

1720407 bp

Protein-coding Genes

1754 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
iron iii abc transporter, periplasmic iron-binding proteinHPHPA9_0001Not AvailableNegative46 - 51017107.9
iron complex transport system substrate-binding domain proteinHPHPA9_0002Not AvailableNegative543 - 7015857.28
iron(iii) abc transporter, periplasmic iron-binding proteinHPHPA9_0003Not AvailableNegative902 - 190337320.8
alkyl hydroperoxide reductase c22 proteinHPHPA9_0004P21762Positive2143 - 273922223.8
outer membrane lipoproteinHPHPA9_0005Q9CK95Positive2893 - 370830140.7
hypothetical proteinHPHPA9_0006Not AvailablePositive3736 - 39247260.34
hypothetical proteinHPHPA9_0007Not AvailableNegative3931 - 40444441.42
penicillin-binding protein 2HPHPA9_0008P44469Negative4201 - 594365738.7
hypothetical proteinHPHPA9_0009Not AvailableNegative5948 - 639117357.9
ribosome biogenesis gtp-binding protein ysxcHPHPA9_0010B5Z9J7Negative6404 - 703023573.6

Displaying genes 1 – 10 of 1797 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites

Health Effects

No health effects information available for this bacterium.