Faecalibacterium prausnitzii M21/2

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii M21/2 is a Gram-positive, non-motile, rod-shaped bacterium that thrives in multiple habitats as a chemoheterotroph. It requires anaerobic conditions for growth and is classified as mesophilic, with an optimal growth temperature of 37°C. Notably, F. prausnitzii M21/2 does not form spores, which is a characteristic trait of this species. This bacterium is significant in the context of the human gut microbiome, where it is commonly found. Its presence is often associated with beneficial effects on host health, including the maintenance of gut homeostasis and anti-inflammatory properties. The absence or reduced levels of F. prausnitzii have been linked to various gastrointestinal disorders. The organism's adaptation to anaerobic environments and its metabolic capabilities allow it to utilize complex polysaccharides as energy sources, contributing to the fermentation processes in the gut. This not only aids in nutrient absorption for the host but also plays a role in the production of short-chain fatty acids, which are vital for colon health. In summary, Faecalibacterium prausnitzii M21/2 exemplifies a key player in gut microbiota, demonstrating how specific microbial traits, such as anaerobic metabolism and the ability to thrive in diverse environments, underpin its ecological role and potential health benefits to the host.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
StrainM21/2

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Faecalibacterium prausnitzii M21/2
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii M21/2


Gene Summary

Adenine Count

679631 bp

Thymine Count

688766 bp

Guanine Count

880431 bp

Cytosine Count

878155 bp

Genome Length

3126983 bp

Protein-coding Genes

3425 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1325490 - 1325501Not Available
Hypothetical proteinFAEPRAM212_01530Not AvailablePositive1329208 - 13294268204.94
hypothetical proteinFAEPRAM212_01531Not AvailablePositive1329419 - 13296438291.29
hypothetical proteinFAEPRAM212_01532Not AvailablePositive1329742 - 13299698811.75
hypothetical proteinFAEPRAM212_01533Not AvailablePositive1329973 - 13301797829.56
Hypothetical proteinFAEPRAM212_01534Not AvailablePositive1330176 - 13303767607.27
Tail-associated lysinFAEPRAM212_01535Not AvailableNegative1330599 - 133128224856.7
HolinFAEPRAM212_01536Not AvailableNegative1331319 - 133164511772.7
Lysis related proteinFAEPRAM212_01537Not AvailableNegative1331661 - 133193910068.2
Hypothetical proteinFAEPRAM212_01538Not AvailableNegative1331929 - 13321237051.27

Displaying genes 1 – 10 of 23 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

348 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da

Displaying 1–10 of 348 metabolites

Health Effects

No health effects information available for this bacterium.