Clostridium botulinum C/D str. It1

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium botulinum C/D str. It1 is a Gram-positive, rod-shaped bacterium known for its anaerobic metabolism and chemoorganotrophic energy source. This species can be found in diverse habitats, indicating its adaptability to various environmental conditions. The cells typically arrange in pairs, singles, or chains, and exhibit mobility due to the presence of flagella. C. botulinum C/D str. It1 thrives optimally at 37°C, fitting within a mesophilic temperature range. Its unique physiological traits, such as having three replicons and a single membrane, contribute to its survival and replication in anaerobic environments. The organism is classified as free-living, highlighting its ability to exist independently in various ecological niches. The presence of multiple accessions, including JENO00000000.1, NZ_CM003329.1, and NZ_CM003330.1, indicates ongoing research and interest in understanding the genetic and functional diversity of this strain. The ecological insight from this bacterium's traits suggests that its adaptability and mobility may play significant roles in its survival and potential impact on human health, particularly due to its association with botulinum toxin production. Understanding these characteristics can inform both microbiological research and public health strategies regarding the prevention of botulism.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium botulinum
StrainC/D It1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium botulinum C/D str. It1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles - Chains
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridium botulinum C/D str. It1 plasmid p4CbIt1, whole genome

Gene Summary

Adenine Count

817417 bp

Thymine Count

967238 bp

Guanine Count

294763 bp

Cytosine Count

420288 bp

Genome Length

2499706 bp

Protein-coding Genes

2166 genes

Non-Coding Genes

182 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinZ963_p0011Not AvailablePositive2439933 - 244023811246.9
Abrb family transcriptional regulatorZ963_p0012Not AvailablePositive2440240 - 24404829175.39
hypothetical proteinZ963_p0013Not AvailablePositive2440475 - 24406968585.81
Rect family recombinaseZ963_p0014Not AvailablePositive2440684 - 244158934027.3
Gp51Z963_p0015Not AvailablePositive2441601 - 244231127037.5
hypothetical proteinZ963_p0016Not AvailablePositive2442314 - 24424786100.72
hypothetical proteinZ963_p0017Not AvailablePositive2442478 - 24426365917.25
Hnh endonucleaseZ963_p0018Not AvailablePositive2442611 - 244314420846.3
Putative single stranded dna binding proteinZ963_p0019Not AvailablePositive2443147 - 244355715576.3
Hypothetical proteinZ963_p0020Not AvailablePositive2443572 - 244413222245.6

Displaying genes 81 – 90 of 2436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

464 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da

Displaying 1–10 of 464 metabolites

Health Effects

No health effects information available for this bacterium.