Streptomyces rapamycinicus NRRL 5491

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces rapamycinicus NRRL 5491 is a notable actinobacterium characterized by its ability to produce the antibiotic rapamycin. A key trait of this organism is its flagella presence, which contributes to its motility. It thrives at an optimal temperature of 29°C and is classified as mesophilic, indicating that it prefers moderate temperature environments for growth. This species is spore-forming, allowing it to survive in adverse conditions and facilitating its dispersal in various ecological niches. Notably, it possesses a single replicon, which may influence its genetic stability and the regulation of its metabolic processes. The unique characteristics of Streptomyces rapamycinicus NRRL 5491 position it as an important player in soil microbiomes, where it can compete with other microorganisms and contribute to the cycling of nutrients. Its ability to produce bioactive compounds such as rapamycin not only highlights its ecological role in soil health but also underscores its potential applications in medicine and agriculture. By understanding the traits of this organism, researchers can further explore its contributions to antibiotic production and its interactions within microbial communities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces rapamycinicus
StrainNRRL 5491

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptomyces rapamycinicus NRRL 5491
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature29
Temperature rangemesophilic
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
Sporulationspore-forming
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces rapamycinicus NRRL 5491 unitig_3_quiver_34, whole

Gene Summary

Adenine Count

1837975 bp

Thymine Count

1829331 bp

Guanine Count

4488383 bp

Cytosine Count

4507510 bp

Genome Length

12663199 bp

Protein-coding Genes

10131 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
squalene synthase hpndD3C57_132425Not AvailablePositive7827962 - 782891234126.7
squalene-associated fad-dependent desaturaseD3C57_132430Not AvailablePositive7828909 - 783034250599.6
dimethylallyltransferaseD3C57_132435Not AvailablePositive7830606 - 783170338885.8
squalene-hopene cyclaseD3C57_132440Not AvailablePositive7831808 - 783375472151.7
1-hydroxy-2-methyl-2-butenyl 4-diphosphate reductaseD3C57_132445Not AvailablePositive7833754 - 783451525539.6
hopanoid biosynthesis associated radical sam protein hpnhD3C57_132450Not AvailablePositive7834466 - 783549138602.6
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthaseD3C57_132455Not AvailablePositive7835520 - 783668640689.2
1-deoxy-d-xylulose-5-phosphate synthaseD3C57_132460Not AvailablePositive7836710 - 783867769564.4
aminotransferaseD3C57_132465Not AvailablePositive7838674 - 784008351738.4
hypothetical proteinD3C57_132470Not AvailablePositive7840101 - 784129440737.4

Displaying genes 6601 – 6610 of 10306 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

3 records
Metabolite IDMetabolite nameStructureCAS number
BASm0039633Clostridium botulinumNot available56-87-1Not available
BASm0039965Anaerostipes hadrus DSM 3319Not available55508-12-8Not available
BASm0040037Clostridium sticklandii DSM 519Not availableNot availableNot available

Displaying 1–3 of 3 metabolites

Health Effects

No health effects information available for this bacterium.