Streptomyces rapamycinicus NRRL 5491

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces rapamycinicus NRRL 5491 is a notable actinobacterium characterized by its ability to produce the antibiotic rapamycin. A key trait of this organism is its flagella presence, which contributes to its motility. It thrives at an optimal temperature of 29°C and is classified as mesophilic, indicating that it prefers moderate temperature environments for growth. This species is spore-forming, allowing it to survive in adverse conditions and facilitating its dispersal in various ecological niches. Notably, it possesses a single replicon, which may influence its genetic stability and the regulation of its metabolic processes. The unique characteristics of Streptomyces rapamycinicus NRRL 5491 position it as an important player in soil microbiomes, where it can compete with other microorganisms and contribute to the cycling of nutrients. Its ability to produce bioactive compounds such as rapamycin not only highlights its ecological role in soil health but also underscores its potential applications in medicine and agriculture. By understanding the traits of this organism, researchers can further explore its contributions to antibiotic production and its interactions within microbial communities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces rapamycinicus
StrainNRRL 5491

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptomyces rapamycinicus NRRL 5491
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature29
Temperature rangemesophilic
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
Sporulationspore-forming
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces rapamycinicus NRRL 5491 unitig_3_quiver_34, whole

Gene Summary

Adenine Count

1837975 bp

Thymine Count

1829331 bp

Guanine Count

4488383 bp

Cytosine Count

4507510 bp

Genome Length

12663199 bp

Protein-coding Genes

10131 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ppx/gppa phosphataseD3C57_114445Not AvailableNegative3646681 - 364722919390.0
septum formation initiatorD3C57_114450Not AvailableNegative3647300 - 364778217939.3
phosphopyruvate hydrataseD3C57_114455Not AvailableNegative3647887 - 364916745547.5
transglycosylaseD3C57_114460Not AvailableNegative3649398 - 365009323829.0
transglycosylaseD3C57_114465Not AvailableNegative3650523 - 365152133789.4
cytochrome p450D3C57_114470Not AvailableNegative3651707 - 365298447495.6
histidine kinaseD3C57_114475Not AvailablePositive3653636 - 365478740912.3
hypothetical proteinD3C57_114480Not AvailablePositive3654784 - 365518514161.9
hypothetical proteinD3C57_114485Not AvailablePositive3655182 - 365555313117.8
atp/gtp-binding proteinD3C57_114490Not AvailablePositive3655528 - 365611821793.1

Displaying genes 3071 – 3080 of 10306 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

3 records
Metabolite IDMetabolite nameStructureCAS number
BASm0039633Clostridium botulinumNot available56-87-1Not available
BASm0039965Anaerostipes hadrus DSM 3319Not available55508-12-8Not available
BASm0040037Clostridium sticklandii DSM 519Not availableNot availableNot available

Displaying 1–3 of 3 metabolites

Health Effects

No health effects information available for this bacterium.