Streptomyces rapamycinicus NRRL 5491

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces rapamycinicus NRRL 5491 is a notable actinobacterium characterized by its ability to produce the antibiotic rapamycin. A key trait of this organism is its flagella presence, which contributes to its motility. It thrives at an optimal temperature of 29°C and is classified as mesophilic, indicating that it prefers moderate temperature environments for growth. This species is spore-forming, allowing it to survive in adverse conditions and facilitating its dispersal in various ecological niches. Notably, it possesses a single replicon, which may influence its genetic stability and the regulation of its metabolic processes. The unique characteristics of Streptomyces rapamycinicus NRRL 5491 position it as an important player in soil microbiomes, where it can compete with other microorganisms and contribute to the cycling of nutrients. Its ability to produce bioactive compounds such as rapamycin not only highlights its ecological role in soil health but also underscores its potential applications in medicine and agriculture. By understanding the traits of this organism, researchers can further explore its contributions to antibiotic production and its interactions within microbial communities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces rapamycinicus
StrainNRRL 5491

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptomyces rapamycinicus NRRL 5491
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature29
Temperature rangemesophilic
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
Sporulationspore-forming
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces rapamycinicus NRRL 5491 unitig_3_quiver_34, whole

Gene Summary

Adenine Count

1837975 bp

Thymine Count

1829331 bp

Guanine Count

4488383 bp

Cytosine Count

4507510 bp

Genome Length

12663199 bp

Protein-coding Genes

10131 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
regulatory protein lysrD3C57_105540Not AvailableNegative1490042 - 149113940000.3
serine/threonine protein kinaseD3C57_105545Not AvailablePositive1491382 - 149269546738.4
penicillin acylaseD3C57_105550Not AvailableNegative1492746 - 1495580101484.0
hypothetical proteinD3C57_105555Not AvailablePositive1495781 - 149639222825.6
maoc family dehydrataseD3C57_105560Not AvailablePositive1496665 - 149712616706.9
tetr family transcriptional regulatorD3C57_105565Not AvailableNegative1497117 - 149775222824.0
aminobenzoate synthetaseD3C57_105570Not AvailableNegative1497808 - 149994077809.2
3-deoxy-7-phosphoheptulonate synthaseD3C57_105575Not AvailableNegative1499984 - 150116842552.0
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseD3C57_105580Not AvailablePositive1501843 - 150298541483.2
polyprenyl synthetaseD3C57_105585Not AvailablePositive1502982 - 150405538929.4

Displaying genes 1261 – 1270 of 10306 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

3 records
Metabolite IDMetabolite nameStructureCAS number
BASm0039633Clostridium botulinumNot available56-87-1Not available
BASm0039965Anaerostipes hadrus DSM 3319Not available55508-12-8Not available
BASm0040037Clostridium sticklandii DSM 519Not availableNot availableNot available

Displaying 1–3 of 3 metabolites

Health Effects

No health effects information available for this bacterium.