Cutibacterium acnes HL201PA1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes HL201PA1 is a Gram-positive, anaerobic rod-shaped bacterium. It is characterized by the absence of mobility and the presence of flagella, indicating a unique adaptation for its host-associated habitat. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, suggesting its specialization in colonizing human hosts. The bacterium has one replicon and a single membrane, which is typical for its classification within the Cutibacterium genus. As a nonsporulating organism, Cutibacterium acnes HL201PA1 maintains its viability through other survival strategies, rather than forming spores. In terms of its ecological role, Cutibacterium acnes HL201PA1 is free-living while being associated with Homo sapiens. This indicates that it may thrive on the skin and within the sebaceous glands of humans, contributing to the skin microbiome. Its presence is often linked to various skin conditions, including acne, highlighting its significance in human health and disease. Overall, the characteristics of Cutibacterium acnes HL201PA1 demonstrate its adaptation to a host-associated lifestyle, particularly within human environments, emphasizing the complex biotic relationships that exist between humans and their resident microbiota.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
StrainHL201PA1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes HL201PA1
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes HL201PA1 HL201PA1_Cont_84, whole genome

Gene Summary

Adenine Count

509642 bp

Thymine Count

516806 bp

Guanine Count

775188 bp

Cytosine Count

761926 bp

Genome Length

2563562 bp

Protein-coding Genes

2241 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pyrazinamidase/nicotinamidasePAST3_02902Not AvailableNegative607421 - 60800220478.0
putative oxidoreductase proteinPAST3_02907Not AvailablePositive608047 - 60905737229.0
bifunctional pyrimidine regulatory protein pyrr uracil phosphoribosyltransferasePAST3_02912Not AvailablePositive609209 - 60978420945.2
aspartate carbamoyltransferase catalytic subunitPAST3_02917Not AvailablePositive609781 - 61072534775.4
carbamoyl phosphate synthase small subunitPAST3_02932Not AvailablePositive612056 - 61314439365.6
carbamoyl phosphate synthase large subunitPAST3_02937Not AvailablePositive613144 - 616350116649.0
dihydroorotate dehydrogenase electron transfer subunitPAST3_02942Not AvailablePositive616350 - 61714428507.6
dihydroorotate dehydrogenase b, catalytic subunitPAST3_02947Not AvailablePositive617141 - 61806431893.9
orotidine 5'-phosphate decarboxylasePAST3_02952Not AvailablePositive618090 - 61880024321.0
orotate phosphoribosyltransferasePAST3_02957Not AvailablePositive618828 - 61947823074.2

Displaying genes 531 – 540 of 2288 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.