Helicobacter pylori OK310

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori OK310 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This organism typically resides in host-associated habitats, specifically within the gastric mucosa of humans and other mammals. It is noteworthy for its single-cell arrangement and does not exhibit mobility, despite having flagella. H. pylori OK310 thrives optimally at 37°C, falling within the mesophilic temperature range. The bacterium possesses two replicons and is distinguished by having two membranes. Its biotic relationship is classified as free-living, indicating that, while it is commonly found in association with hosts, it may also exist independently under certain conditions. Understanding the characteristics of H. pylori OK310 is crucial, particularly given its role in human health, including its association with gastric disorders. The microaerophilic nature of this bacterium suggests that it requires specific oxygen levels for optimal growth, which aligns with its habitat within the stomach, where oxygen is limited. The presence of two membranes may provide additional protective mechanisms against the acidic environment of the gastric lumen. Overall, H. pylori OK310 serves as an important model for studying host-microbe interactions and the ecological dynamics within the gastric microbiome, highlighting the complex relationships that exist between pathogenic bacteria and their human hosts.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainOK310

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori OK310
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori OK310 plasmid pHPOK310, complete sequence.

Gene Summary

Adenine Count

1424 bp

Thymine Count

1220 bp

Guanine Count

759 bp

Cytosine Count

755 bp

Genome Length

4158 bp

Protein-coding Genes

2 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cytochrome c biogenesis proteinHPOK310_RS05050Not AvailableNegative1055116 - 1057926106149.0
soxw family proteinHPOK310_RS05055Not AvailableNegative1057935 - 105860625673.4
ferrochelataseHPOK310_RS05060Not AvailableNegative1058679 - 105968638680.2
hypothetical proteinHPOK310_RS05065Not AvailablePositive1059742 - 106017316431.2
16s rrna (uracil(1498)-n(3))-methyltransferaseHPOK310_RS05070Not AvailablePositive1060174 - 106085425782.4
outer membrane beta-barrel proteinHPOK310_RS05075Not AvailableNegative1060878 - 106295977088.0
dctp deaminaseHPOK310_RS05080Not AvailableNegative1063120 - 106368620903.2
acetyl-coa carboxylase biotin carboxyl carrier proteinHPOK310_RS05085Not AvailablePositive1063817 - 106428717205.1
acetyl-coa carboxylase biotin carboxylase subunitHPOK310_RS05090Not AvailablePositive1064293 - 106566050712.4
type ii dna modification enzymeHPOK310_RS05095Not AvailablePositive1065753 - 106671537437.0

Displaying genes 1011 – 1020 of 1545 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.