Porphyromonas gingivalis JCVI SC001

Porphyromonas gingivalis JCVI SC001 is a Gram-negative, rod-shaped bacterium that is primarily associated with host environments, indicating its role as an opportunistic pathogen in humans. It is classified as an anaerobe, meaning it requires low oxygen levels for survival and growth, thriving optimally at a temperature of 37°C, which aligns with the human body temperature. This organism is mesophilic, with a temperature range that supports growth in moderate thermal conditions. P. gingivalis JCVI SC001 is non-motile and possesses flagella, although its mobility is limited. The bacterium has two replicons and two membranes, consistent with its Gram-negative classification. Notably, it is a free-living organism that does not undergo sporulation, which influences its survival strategies and ecological interactions. With accessions APMB00000000.1 and NZ_CM001843.1, P. gingivalis JCVI SC001 is well-documented within microbial databases, providing valuable genetic information for further studies. This organism is significant in the context of periodontal disease, where it contributes to the dysbiosis of oral microbiota. Its ability to thrive in anaerobic conditions and its association with host tissues highlight its ecological role as a pathogenic bacterium in the oral cavity, leading to inflammation and tissue destruction. Understanding the characteristics and behaviors of P. gingivalis JCVI SC001 can enhance insights into microbial-host interactions and the development of targeted therapies for periodontal diseases.