Helicobacter pylori FD423

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori FD423 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spirilla shape. It is host-associated, indicating its ecological niche is within a host organism. This strain exhibits a single-cell arrangement and possesses flagella, contributing to its mobility, although the description notes that it is non-motile under certain conditions. H. pylori FD423 thrives optimally at 37°C, falling within the mesophilic temperature range. It has a unique genetic structure, consisting of one replicon and two membranes. Despite being described as free-living, its association with a host suggests a complex biotic relationship, potentially influencing host health and disease. This bacterium is significant in the context of human health, particularly in relation to gastric conditions, as H. pylori is known to be a common inhabitant of the human stomach. The ecological insight here emphasizes the adaptability of H. pylori FD423 to specific environments, such as the gastric niche, where it can survive and thrive, potentially leading to pathogenic outcomes. Understanding its traits, such as microaerophilic requirements and optimal growth temperature, can provide valuable information for studying its role in human health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainFD423

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori FD423
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori FD423 contig99, whole genome shotgun sequence.

Gene Summary

Adenine Count

494087 bp

Thymine Count

493634 bp

Guanine Count

314904 bp

Cytosine Count

320501 bp

Genome Length

1623128 bp

Protein-coding Genes

1625 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinN402_04965Not AvailablePositive856058 - 8561563692.83
phospho-2-dehydro-3-deoxyheptonate aldolaseN402_04970Not AvailablePositive856261 - 85748045891.4
urease subunit alphaN402_00265Not AvailablePositive857708 - 85854931211.2
hypothetical proteinN402_00270Not AvailableNegative858555 - 8586865073.35
acid-activated urea channelN402_00275Not AvailablePositive858742 - 85932921682.6
urease accessory protein ureeN402_00280Not AvailablePositive859331 - 85984319325.6
urease accessory protein urefN402_00285Not AvailablePositive859887 - 86063928202.9
hypothetical proteinN402_00290Not AvailablePositive860668 - 8608867987.77
hypothetical proteinN402_04985Not AvailablePositive860887 - 8609652928.38
peroxiredoxinN402_04995Not AvailableNegative861198 - 86165617102.8

Displaying genes 851 – 860 of 1668 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.