Actinomyces naeslundii str. Howell 279

Gram-positiveFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Actinomyces

Description

Actinomyces naeslundii str. Howell 279 is a gram-positive, rod-shaped bacterium that thrives in a mesophilic temperature range, classified as a chemoheterotroph. This microbe primarily inhabits the human oral cavity, yet has been isolated from other body sites such as the gastrointestinal tract and respiratory tract. A. naeslundii is considered an obligate anaerobe, meaning it requires an oxygen-free environment for optimal growth, and it is commonly found in biofilms associated with dental plaque. As a gram-positive organism, A. naeslundii retains the crystal violet stain used in the Gram staining procedure, resulting in a deep purple appearance under a microscope. This characteristic is indicative of a thick peptidoglycan layer in its cell wall, which provides structural strength and plays a role in its pathogenic potential. The rod-shaped morphology is typical for many species within the Actinomyces genus, allowing for efficient colonization and interaction with other microbes. Being a chemoheterotroph, A. naeslundii derives its energy and carbon from organic compounds, which it accesses in the nutrient-rich environments of the human body. Its anaerobic nature facilitates its survival in low-oxygen niches, allowing it to coexist with other microorganisms in the complex and dynamic oral microbiome. This microbe plays a crucial role in dental health, as it contributes to the formation of dental plaque, a precursor to caries and periodontal diseases. Moreover, A. naeslundii has been studied for its potential applications in biotechnology and medicine, given its enzymatic capabilities and interactions with other microbial species in the human microbiome. Its unique properties make it a subject of interest in research related to oral health and microbial ecology.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusActinomyces
SpeciesActinomyces naeslundii
StrainHowell 279

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Actinomyces naeslundii str. Howell 279
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Actinomyces naeslundii str. Howell 279


Gene Summary

Adenine Count

507318 bp

Thymine Count

493841 bp

Guanine Count

1059140 bp

Cytosine Count

1054029 bp

Genome Length

3114341 bp

Protein-coding Genes

2930 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+352 - 468Not Available
transporter, major facilitator domain proteinHMPREF1129_1290Not Available-1 - 53817968.0
hypothetical proteinHMPREF1129_1291Not Available-585 - 6984042.79
Ncrna_class:srp_rnaNot AvailableNot Available+1882 - 1979Not Available
mfs transporter, sp familyHMPREF1129_1292Not Available-773 - 222751897.7
16s ribosomal rnaNot AvailableNot Available+2844 - 4294Not Available
putative protein iolhHMPREF1129_1293Not Available-2423 - 329533349.8
oxidoreductase, nad-binding domain proteinHMPREF1129_1294Not Available-3602 - 461236776.5
ap endonuclease, family 2HMPREF1129_1295Not Available-4675 - 560434887.1
methylmalonate-semialdehyde dehydrogenase (acylating)HMPREF1129_1296Not Available-5825 - 731853215.6

Displaying genes 1 – 10 of 2988 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

247 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0002143menaquinone-7C46H64O2Chemical structure of menaquinone-7Not available
Average648.9992Da
Monoisotopic648.4906313Da

Displaying 1–10 of 247 metabolites