Leptospira interrogans str. UI 12621

Leptospira interrogans str. UI 12621 is a Gram-negative bacterium classified within the genus Leptospira. This organism exhibits a spirilla shape and is characterized as an aerobic microbe, requiring oxygen for growth. L. interrogans str. UI 12621 is host-associated, indicating its lifecycle involves a specific host environment. This strain has a mesophilic temperature range, with an optimal growth temperature of 28°C. It possesses a unique cellular structure with two membranes, consistent with its Gram-negative classification. Additionally, the bacterium contains one replicon, which is indicative of its genetic organization. Notably, L. interrogans str. UI 12621 has flagella, which are typically associated with motility. However, this strain is described as non-motile, suggesting that while it may have the structural components for mobility, it does not exhibit movement. The ecological insights into L. interrogans str. UI 12621 highlight its association with hosts, which can play a significant role in the epidemiology of leptospirosis, a disease caused by this pathogen. Understanding the specific habitat and physiological traits of this strain can inform public health strategies and facilitate targeted research on its biology and pathogenic mechanisms. The reference accession number for this strain is AHNQ00000000.2, which provides a pathway for further genomic and functional studies.