Cupriavidus necator N-1

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Cupriavidus

Description

Cupriavidus necator N-1 is a Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This organism thrives in freshwater and soil habitats, exhibiting a dual energy metabolism as both a heterotroph and chemolithoautotroph. C. necator N-1 is aerobic, requiring oxygen for its metabolic processes, and it is classified as mesophilic, with an optimal growth temperature of 30°C. The bacterium possesses four replicons and two membranes, which is typical for this group of microorganisms. Its free-living biotic relationship indicates that it does not rely on a host for survival, thereby contributing to nutrient cycling in its environment. Importantly, C. necator N-1 is not pathogenic, making it a potential candidate for studies in bioremediation or other applications where non-pathogenic microbes are preferred. The ecological role of C. necator N-1 can be significant in nutrient-poor environments, where its ability to utilize inorganic compounds for energy may help in the degradation of pollutants and the recycling of essential nutrients. This feature highlights its importance in maintaining ecosystem balance and promoting soil health, particularly in freshwater systems. The organism's various genomic accessions (NC_015726.1, NC_015723.1, NC_015724.1, NC_015727.1) may provide further insights into its metabolic pathways and ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusCupriavidus
SpeciesCupriavidus necator
StrainN-1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Cupriavidus necator N-1
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperature30
Temperature rangeMesophilic
HabitatFresh water - Soil
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceHeterotroph - Chemolithoautotroph
PathogenicityNo

Genome Summary

Cupriavidus necator N-1 plasmid pBB1, complete sequence.

Gene Summary

Adenine Count

290866 bp

Thymine Count

288033 bp

Guanine Count

461624 bp

Cytosine Count

458652 bp

Genome Length

1499175 bp

Protein-coding Genes

1412 genes

Non-Coding Genes

2 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoyl synthaseCNE_RS00565Not AvailablePositive114887 - 11588237010.4
5-oxoprolinase subunit pxpbCNE_RS00570Not AvailablePositive116124 - 11677122898.4
biotin-dependent carboxyltransferase family proteinCNE_RS00575Not AvailablePositive116768 - 11778735821.2
5-oxoprolinase subunit pxpaCNE_RS00580Not AvailablePositive117843 - 11858326656.7
duf969 domain-containing proteinCNE_RS00585Not AvailablePositive118684 - 11941225939.7
duf979 domain-containing proteinCNE_RS00590Not AvailablePositive119423 - 12037333574.6
pyroglutamyl-peptidase iCNE_RS00595Not AvailablePositive120389 - 12103922766.4
vanz family proteinCNE_RS00600Not AvailableNegative121051 - 12230145873.3
abc-type transport auxiliary lipoprotein family proteinCNE_RS00605Not AvailableNegative122321 - 12296822990.5
mlad family proteinCNE_RS00610Not AvailableNegative123021 - 12396233515.8

Displaying genes 4451 – 4460 of 7968 in total

Metabolites

1766 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm00005166-deoxyerythronolide BC21H38O6Chemical structure of 6-deoxyerythronolide BNot available
Average386.5228Da
Monoisotopic386.2668389Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm00005992,5-dihydroxypyridineC5H5NO2Chemical structure of 2,5-dihydroxypyridineNot available
Average111.1Da
Monoisotopic111.0320284Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da

Displaying 1–10 of 1766 metabolites

Health Effects

No health effects information available for this bacterium.