Treponema denticola ATCC 35404

Treponema denticola ATCC 35404 is a Gram-negative, anaerobic bacterium belonging to the genus Treponema. This species exhibits a spirilla shape and is characterized by its single-cell arrangement. It possesses two membranes and two replicons, indicating a unique genetic structure among bacteria. T. denticola is free-living, suggesting that it can exist independently in its environment, yet it is typically found in association with hosts. This organism thrives optimally at a temperature of 30°C and falls within the mesophilic temperature range, indicating its preference for moderate temperatures conducive to growth. Notably, T. denticola does not exhibit mobility despite having flagella, which may serve other functions beyond motility in this context. Understanding the habitat and characteristics of Treponema denticola ATCC 35404 provides insights into its ecological role. As a free-living anaerobe in host-associated environments, it may contribute to the microbial communities found in the oral cavity, where it is often implicated in periodontal diseases. The presence of this bacterium in such environments underscores its potential influence on host health and the dynamics of microbial interactions within the oral microbiome. The dual nature of its free-living lifestyle and association with hosts highlights its adaptability and ecological significance in maintaining the balance of microbial populations in specific habitats.