Helicobacter pylori Hp P-25

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-25 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, which aligns with the physiological temperature of its host. As a host-associated microbe, H. pylori is predominantly found in the gastric environment of humans, where it plays a complex role in gastrointestinal health. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its adaptation to the gastric niche, where local oxygen concentrations are lower than in the atmosphere. This adaptation allows H. pylori to maintain its metabolic processes within the hostile environment of the stomach, where it can interact with gastric epithelial cells and the host immune response. An intriguing aspect of Helicobacter pylori Hp P-25 is its potential role in influencing the gastric microbiome. By occupying a distinct niche within the stomach, it may affect the overall microbial diversity and function of the gastric ecosystem, thereby influencing various physiological processes in the host. Further studies are warranted to elucidate the specific interactions between H. pylori and other microbial communities in the gastrointestinal tract, as well as its implications for host health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-25

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-25
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-25


Gene Summary

Adenine Count

503507 bp

Thymine Count

510319 bp

Guanine Count

324673 bp

Cytosine Count

328962 bp

Genome Length

1667461 bp

Protein-coding Genes

1809 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Hypothetical proteinHPHPP25_0461Not Available-420739 - 42150628561.8
Hypothetical proteinHPHPP25_0462I7H0I4-421565 - 42243132720.6
Hypothetical proteinHPHPP25_0463Not Available-422446 - 42333033777.6
Hypothetical proteinHPHPP25_0464Not Available-423385 - 42371112734.6
Hypothetical proteinHPHPP25_0465Not Available-423711 - 42424420727.6
Hypothetical proteinHPHPP25_0466Not Available-424270 - 42506429608.3
Hypothetical proteinHPHPP25_0467Not Available-425068 - 42561320881.0
Hypothetical proteinHPHPP25_0468Not Available-425660 - 4258848542.62
Hypothetical proteinHPHPP25_0469Not Available-425881 - 42686137814.0
Phage holin3 superfamily proteinHPHPP25_0470Not Available-426865 - 42718811988.9

Displaying genes 1 – 10 of 1873 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites