Helicobacter pylori Hp P-8

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-8 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spirilla shape. It is typically found in a host-associated habitat, indicating a close relationship with its host organism. This bacterium is notable for having a single cell arrangement and is free-living, despite its association with hosts. Hp P-8 possesses flagella, which contribute to its motility, although the organism itself is described as non-motile in some contexts. Its optimal growth temperature is 37°C, which falls within the mesophilic temperature range, suggesting it thrives in moderate temperature conditions typical of warm-blooded hosts. Additionally, it has a unique cellular structure, consisting of two membranes and a single replicon, which is indicative of its genetic organization. The presence of Helicobacter pylori in the gastric environment of hosts is significant due to its established role in various gastrointestinal diseases, including gastritis and peptic ulcers. The bacterium's adaptation to a microaerophilic environment allows it to survive in the oxygen-limited conditions of the stomach, where it can influence the host's health. Understanding the traits of Hp P-8 can provide insights into its ecological role in host-associated environments and its impact on human health. The accession number for this strain is AKPM00000000.1, which can be used for further reference in genomic studies.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-8

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-8
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-8


Gene Summary

Adenine Count

489051 bp

Thymine Count

492584 bp

Guanine Count

316577 bp

Cytosine Count

317414 bp

Genome Length

1615626 bp

Protein-coding Genes

1628 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinHPHPP8_0079Not AvailablePositive77667 - 778195630.92
hypothetical proteinHPHPP8_0080Not AvailableNegative77918 - 780464668.79
transcription antitermination factor nusbHPHPP8_0081B6JPA0Negative78217 - 7863315564.0
6,7-dimethyl-8-ribityllumazine synthaseHPHPP8_0082B6JPA1Negative78635 - 7910516919.6
3-deoxy-8-phosphooctulonate synthaseHPHPP8_0083B6JPA2Negative79115 - 7994530257.6
carbonic anhydraseHPHPP8_0084Q9ZN54Negative79932 - 8059725717.7
orotidine 5'-phosphate decarboxylaseHPHPP8_0085B6JPA4Positive80719 - 8140225407.3
pantoate--beta-alanine ligaseHPHPP8_0086Q1CVE9Positive81403 - 8223331002.9
Trna-gluNot AvailableNot AvailablePositive82247 - 82322Not Available
Trna-aspNot AvailableNot AvailablePositive82385 - 82461Not Available

Displaying genes 81 – 90 of 1669 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.