Helicobacter pylori Hp H-3

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-3 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and the presence of flagella. It is notable for its habitat, which is associated with specific hosts, indicating a specialized ecological niche. The organism exists as single cells rather than in clusters or chains. H. pylori Hp H-3 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. This preference for moderate temperatures aligns with its association with warm-blooded hosts, where it can effectively colonize the gastric mucosa. The bacterium possesses a single replicon and is encased by two membranes, a characteristic feature of Gram-negative bacteria. Despite being free-living, H. pylori typically resides in the stomachs of its hosts, where it can have significant implications for gastrointestinal health. The presence of flagella contributes to its motility, enabling it to navigate the viscous environment of the gastric mucus. This organism is of particular interest due to its role in various gastric diseases, including peptic ulcers and gastric cancer. Understanding its traits, such as its microaerophilic nature and optimal growth conditions, can provide insights into its pathogenic mechanisms and interactions with the host immune system. The ecological relationship between H. pylori and its host is complex and highlights the importance of this bacterium in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-3

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-3
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-3


Gene Summary

Adenine Count

522427 bp

Thymine Count

523129 bp

Guanine Count

334445 bp

Cytosine Count

332041 bp

Genome Length

1712042 bp

Protein-coding Genes

1682 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinHPHPH3_0455Not AvailablePositive427945 - 42860724378.8
flagellar m-ring protein flifHPHPH3_0456Not AvailablePositive428651 - 43035463698.3
23s ribosomal rnaNot AvailableNot AvailablePositive430293 - 433176Not Available
flagellar motor switch protein fligHPHPH3_0457Not AvailablePositive430373 - 43140438328.4
putative flagellar assembly proteinHPHPH3_0458Not AvailablePositive431397 - 43216728962.7
1-deoxy-d-xylulose-5-phosphate synthaseHPHPH3_0459Not AvailablePositive432170 - 43402067532.5
5s ribosomal rnaNot AvailableNot AvailablePositive433419 - 433534Not Available
gtp-binding protein lepaHPHPH3_0460Not AvailablePositive434041 - 43583166042.2
cytosine-specific methyltransferaseHPHPH3_0461Not AvailablePositive435840 - 43676935546.2
hypothetical proteinHPHPH3_0462Not AvailablePositive436996 - 4372329099.76

Displaying genes 461 – 470 of 1729 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.