Helicobacter pylori Hp H-3

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-3 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and the presence of flagella. It is notable for its habitat, which is associated with specific hosts, indicating a specialized ecological niche. The organism exists as single cells rather than in clusters or chains. H. pylori Hp H-3 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. This preference for moderate temperatures aligns with its association with warm-blooded hosts, where it can effectively colonize the gastric mucosa. The bacterium possesses a single replicon and is encased by two membranes, a characteristic feature of Gram-negative bacteria. Despite being free-living, H. pylori typically resides in the stomachs of its hosts, where it can have significant implications for gastrointestinal health. The presence of flagella contributes to its motility, enabling it to navigate the viscous environment of the gastric mucus. This organism is of particular interest due to its role in various gastric diseases, including peptic ulcers and gastric cancer. Understanding its traits, such as its microaerophilic nature and optimal growth conditions, can provide insights into its pathogenic mechanisms and interactions with the host immune system. The ecological relationship between H. pylori and its host is complex and highlights the importance of this bacterium in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-3

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-3
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-3


Gene Summary

Adenine Count

522427 bp

Thymine Count

523129 bp

Guanine Count

334445 bp

Cytosine Count

332041 bp

Genome Length

1712042 bp

Protein-coding Genes

1682 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative nickel-responsive regulatorHPHPH3_1533Not AvailableNegative1512351 - 151279717211.3
tonb-system energizer exbbHPHPH3_1534Not AvailablePositive1513108 - 151354515926.1
tonb system transport protein exbdHPHPH3_1535Not AvailablePositive1513542 - 151393114347.3
periplasmic protein tonbHPHPH3_1536Not AvailablePositive1513897 - 151474531239.5
outer membrane protein hopn2HPHPH3_1537Not AvailablePositive1514935 - 151701676146.4
mannonate dehydrataseHPHPH3_1538Not AvailableNegative1517172 - 151790027116.6
magnesium and cobalt transport protein coraHPHPH3_1539Not AvailableNegative1517907 - 151886337121.6
phosphoglycerate kinaseHPHPH3_1540Not AvailableNegative1518879 - 152008744693.2
glyceraldehyde-3-phosphate dehydrogenase, type iHPHPH3_1541Not AvailableNegative1520103 - 152109536027.4
uracil-dna glycosylaseHPHPH3_1542Not AvailableNegative1521184 - 152188526255.3

Displaying genes 1531 – 1540 of 1729 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.